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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 14, 2025; 31(46): 113145
Published online Dec 14, 2025. doi: 10.3748/wjg.v31.i46.113145
Published online Dec 14, 2025. doi: 10.3748/wjg.v31.i46.113145
Endo-hepatology: Bridging the gap between lumen and liver
Walaa Abdelhamed, Department of Endemic Medicine, Sohag University, Sohag 14322, Egypt
Mohamed El-Kassas, Department of Endemic Medicine, Faculty of Medicine, Helwan Univer
Mohamed El-Kassas, Applied Science Research Center, Applied Science Private University, Amman 11931, Jordan
Co-first authors: Walaa Abdelhamed and Mohamed El-Kassas.
Author contributions: Abdelhamed W drafted the manuscript; El-Kassas M conceptualized the idea and revised the final manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mohamed El-Kassas, MD, Full Professor, Department of Endemic Medicine, Faculty of Medicine, Helwan University, Ain Helwan, Cairo 11795, Egypt.
Received: August 18, 2025
Revised: September 16, 2025
Accepted: October 28, 2025
Published online: December 14, 2025
Processing time: 116 Days and 13.8 Hours
Revised: September 16, 2025
Accepted: October 28, 2025
Published online: December 14, 2025
Processing time: 116 Days and 13.8 Hours
Core Tip
Core Tip: Endo-hepatology bridges hepatology and advanced endoscopy, offering minimally invasive, precise tools for managing complex liver conditions. This review outlines key roles of endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography in evaluating portal hypertension, biliary complications, steatotic liver disease, and liver tumors. It also discusses novel methods like EUS-guided portal pressure measurements and artificial intelligence-enhanced imaging. These innovations highlight the growing need for multidisciplinary training and collaborative research to improve patient care.