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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2026; 14(5): 117981
Published online Feb 16, 2026. doi: 10.12998/wjcc.v14.i5.117981
Published online Feb 16, 2026. doi: 10.12998/wjcc.v14.i5.117981
Clinical outcomes of multidrug-resistant organism infections in a tertiary care hospital in India
Pradeep Pandy, Harshita Singh, Prasan Kumar Panda, Division of Internal Medicine, All India Institute of Medical Sciences, Rishikesh 249203, India
Balram Ji Omar, Department of Microbiology, All India Institute of Medical Sciences, Rishikesh 249203, India
Deepa Kumari, Department of Nursing Services, All India Institute of Medical Sciences, Rishikesh 249203, India
Author contributions: Pandy P, Singh H, Omar BJ, and Kumari D were involved in data collection, analysis, writing the draft and approving the draft; Panda PK was responsible for conceptualization, investigation, methodology, resources, critical review, and approval.
Institutional review board statement: The study was approved by the institutional ethics committee, All India Institute of Medical Sciences, Rishikesh, India (No. 28/IEC/IM/NF/2023).
Informed consent statement: Informed consent was waived by the above ethics committee, considering a hospital record-based study.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: It will be made available to others upon request to the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Prasan Kumar Panda, Professor, Division of Internal Medicine, All India Institute of Medical Sciences, Room No. 409, College Block, Rishikesh 249203, India.
Received: December 22, 2025
Revised: January 6, 2026
Accepted: January 26, 2026
Published online: February 16, 2026
Processing time: 52 Days and 10.9 Hours
Revised: January 6, 2026
Accepted: January 26, 2026
Published online: February 16, 2026
Processing time: 52 Days and 10.9 Hours
Core Tip
Core Tip: Multidrug-resistant organisms (MDROs) pose a significant threat to hospital care, particularly in high-burden settings such as India, contributing substantially to antimicrobial resistance-related morbidity and mortality. This study aimed to evaluate clinical outcomes associated with MDRO isolation in a tertiary-care hospital and to identify actionable gaps to strengthen infection prevention and targeted antimicrobial stewardship. A key finding was that while isolation did not significantly reduce mortality among Intensive care unit (ICU) patients, it was associated with significantly longer ICU and hospital length of stay.