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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 16, 2026; 14(2): 116519
Published online Jan 16, 2026. doi: 10.12998/wjcc.v14.i2.116519
Published online Jan 16, 2026. doi: 10.12998/wjcc.v14.i2.116519
Intraosseous lipoma of the sphenoid bone causing optic nerve compression: A case report
Yehya Tlaiss, John Warrak, Department of Ophthalmology, University of Balamand, Beirut 1100, Beyrouth, Lebanon
Layal Abou Zeki, Omar Al-Awar, Department of Neurosurgery, University of Balamand, Beirut 1100, Beyrouth, Lebanon
Hadi Farhat, Department of General Surgery, University of Balamand, Beirut 1100, Beyrouth, Lebanon
Mohamad Yazbeck, Department of Neurosurgery, Lebanese University, Beirut 1100, Beyrouth, Lebanon
Author contributions: Tlaiss Y conceived the study, collected and interpreted ophthalmologic data, and drafted the manuscript; Abou Zeki L planned and performed the neurosurgical procedure and interpreted intraoperative findings; Abou Zeki L, Farhat H, and Yazbeck M critically revised the manuscript; Farhat H assisted in surgery, contributed to perioperative management; Warrak J contributed to clinical data collection, literature review, and drafting of the discussion; Yazbeck M analyzed and interpreted neuroimaging, prepared imaging figures; Al-Awar O supervised overall clinical management, provided senior neurosurgical input, and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yehya Tlaiss, MD, Department of Ophthalmology, University of Balamand, The Backyard Street, Hazmieh, Beirut 1100, Beyrouth, Lebanon.
Received: November 13, 2025
Revised: December 4, 2025
Accepted: December 22, 2025
Published online: January 16, 2026
Processing time: 64 Days and 5.7 Hours
Revised: December 4, 2025
Accepted: December 22, 2025
Published online: January 16, 2026
Processing time: 64 Days and 5.7 Hours
Core Tip
Core Tip: This case report describes a rare intraosseous lipoma of the sphenoid bone causing compressive optic neuropathy and reversible vision loss in a middle-aged patient. Magnetic resonance imaging (MRI) suggested a lipomatous lesion, but definitive diagnosis required intraoperative findings and histopathological confirmation of an adipose tumor of bone. Successful optic nerve decompression led to significant visual recovery. This case underscores the need to consider in