Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Cases. Apr 26, 2026; 14(12): 118091
Published online Apr 26, 2026. doi: 10.12998/wjcc.v14.i12.118091
Published online Apr 26, 2026. doi: 10.12998/wjcc.v14.i12.118091
Laparoscopic cholecystectomy in patients with situs inversus totalis: Two case reports and review of literature
Gajendra Bhati, Department of Surgical Gastroenterology and Hepatopancreatobiliary Surgery, Adesh Institute of Medical Sciences and Research, Bathinda 151001, Punjab, India
Gabriella Teresa Capolupo, Marco Caricato, Filippo Carannante, Unità Operativa Complessa Chirurgia Colorettale, Fondazione Policlinico Campus Bio-Medico, Roma 00128, Italy
Kamna Bhati, Department of Dietetics, All India Institute of Medical Sciences and Research, Bathinda 151001, Punjab, India
Akshansh Gupta, Department of Surgical Gastroenterology, Adesh Institute of Medical Sciences and Research, Bathinda 151001, Punjab, India
Raghav Bansal, Department of General Surgery, Adesh Institute of Medical Sciences and Research, Bathinda 151001, Punjab, India
Polishetti Sai Srinija, Sri Venkata Sai Medical College, Kaloji Narayana Rao University of Health Sciences, Telangana 509001, India
Co-corresponding authors: Raghav Bansal and Filippo Carannante.
Author contributions: Bhati G and Carannante F contributed equally to this manuscript and are co-corresponding authors. Bhati G and Bansal R were involved in patient management and surgical treatment; Caricato M and Capolupo GT provided surgical supervision and critical clinical input; Bhati K, Gupta A, and Srinija S collected clinical data and performed the literature review; Carannante F conceived and designed the study, critically revised the manuscript for important intellectual content, and approved the final version. All authors read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for their participation in the study and for the publication of their clinical information and images. No identifiable patient information is included in this publication.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Filippo Carannante, PhD, Academic Fellow, Additional Professor, FACS, Unità Operativa Complessa Chirurgia Colorettale, Fondazione Policlinico Campus Bio-Medico, Via Alvaro del Portillo 200, Roma 00128, Italy. f.carannante@unicampus.it
Received: December 25, 2025
Revised: February 4, 2026
Accepted: March 19, 2026
Published online: April 26, 2026
Processing time: 112 Days and 8.5 Hours
Revised: February 4, 2026
Accepted: March 19, 2026
Published online: April 26, 2026
Processing time: 112 Days and 8.5 Hours
Core Tip
Core Tip: Situs inversus totalis is a rare anatomical condition that presents unique diagnostic and technical challenges during laparoscopic cholecystectomy. This case series emphasizes the importance of thorough preoperative imaging to clearly define biliary anatomy and identify any associated anomalies. It also highlights the need for careful adaptation of surgical technique, including mirror-image port placement and ergonomic adjustments by the surgical team. Strict adherence to the critical view of safety remains essential to minimize the risk of bile duct injury and to ensure safe, effective, and re