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Meta-Analysis
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2026; 14(1): 116047
Published online Jan 6, 2026. doi: 10.12998/wjcc.v14.i1.116047
Comparing trans-oral endoscopic thyroidectomy vestibular approach and trans-areolar approaches regarding postoperative infections and swallowing difficulty
Hyder Mirghani
Hyder Mirghani, Department of Internal Medicine, University of Tabuk, Tabuk 71421, Saudi Arabia
Author contributions: Mirghani HO conceived and designed the study, conducted the literature search, drafted and made critical revisions to the manuscript, and provided final approval of the version to be published.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hyder Mirghani, MD, Professor, Department of Internal Medicine, University of Tabuk, King Faisal Road, Educational Estate, Tabuk 71421, Saudi Arabia. s.hyder63@hotmail.com
Received: November 2, 2025
Revised: November 25, 2025
Accepted: December 19, 2025
Published online: January 6, 2026
Processing time: 65 Days and 18.5 Hours
Core Tip

Core Tip: Due to the increasing rate of thyroid nodules diagnosis, and the desire to avoid the unsightly cervical scar, remote thyroidectomies were invented and are increasingly performed. Transoral endoscopic thyroidectomy vestibular approach and trans-areolar approaches are the two most commonly used remote approaches. No previous meta-analysis has compared postoperative infections and swallowing difficulties among the two procedures. Therefore, we reviewed the literature on this important topic to the better choice of scarless surgery procedure.