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Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2025; 13(35): 115410
Published online Dec 16, 2025. doi: 10.12998/wjcc.v13.i35.115410
Esophageal fistula after resection of giant mediastinal liposarcoma: A case report
Yi-Zong Ding, Dao-Qiang Tang, Xiao-Jing Zhao
Yi-Zong Ding, Xiao-Jing Zhao, Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Dao-Qiang Tang, Department of Pathology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Author contributions: Ding YZ was responsible for conceptualizing the study and drafting the initial manuscript; Tang DQ was responsible for curating the data; Zhao XJ provided a critical review, edited the manuscript, and supervised the study, provided guidance throughout the writing process; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Jing Zhao, PhD, Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai 200127, China. 18133@renji.com
Received: October 17, 2025
Revised: November 11, 2025
Accepted: December 10, 2025
Published online: December 16, 2025
Processing time: 61 Days and 14.8 Hours
Core Tip

Core Tip: We report a very rare case of giant mediastinal liposarcoma. To the best of our knowledge, this is the first report of bilateral single-port video-assisted thoracoscopic surgery for giant mediastinal liposarcoma and the first report of esophageal fistula after this surgery. This report provided valuable lessons and reference for selection of appropriate surgical approach and the management of postoperative esophageal fistula.