Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2025; 13(33): 112241
Published online Nov 26, 2025. doi: 10.12998/wjcc.v13.i33.112241
Published online Nov 26, 2025. doi: 10.12998/wjcc.v13.i33.112241
Thyroid nodules as predictors of adenomatous colonic polyps: A systematic review and meta-analysis
Hyder Osman Mirghani, Department of Internal Medicine, University of Tabuk, Tabuk 51941, Saudi Arabia
Salah Alghamdi, Department of Surgery, University of Tabuk, Tabuk PO Box 3378 Tabuk 51941, Saudi Arabia
Author contributions: Mirghani HO performed the conception and design of the study, the literature search, the drafting, critical revision, and provided the final approval of the version to be published; Salah A contributed to the literature search, drafting, revision, and approval before submission.
Conflict-of-interest statement: All authors declare that there are no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Check-list.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hyder Osman Mirghani, MD, Full Professor, Department of Internal Medicine, University of Tabuk, Prince Fahd Bin Sulta, Tabuk 51941, Saudi Arabia.
Received: July 22, 2025
Revised: July 25, 2025
Accepted: October 21, 2025
Published online: November 26, 2025
Processing time: 122 Days and 17 Hours
Revised: July 25, 2025
Accepted: October 21, 2025
Published online: November 26, 2025
Processing time: 122 Days and 17 Hours
Core Tip
Core Tip: Thyroid polyps are common among the middle age group, and colonoscopy is indicated in individuals older than 50 years. However, it is invasive, making easy reliable methods for risk stratification for colonic polyps screening important. The few studies that assessed the association of thyroid nodules and colon polyps showed contradicting results. The current meta-analysis contributed significantly to the field because it is the first meta-analysis to find an association. Our research challenges the current colonic polyp screening guidelines because physicians might need to include thyroid nodules as a risk factor for colonic polyps.