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Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2025; 13(32): 110391
Published online Nov 16, 2025. doi: 10.12998/wjcc.v13.i32.110391
Clinicopathologic differences before and after elective laparoscopic cholecystectomy according to obesity
Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Myeong Hun Oh, Su-Bin Song
Byeong Gwan Noh, Myeong Hun Oh, Su-Bin Song, Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan 49241, South Korea
Hyung Il Seo, Young Mok Park, Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Yangsan 44955, South Korea
Author contributions: Noh BG, Seo HI, Park YM, Oh MH, and Song SB contributed to the acquisition of data for this study; Noh BG analyzed the data and wrote the manuscript; Seo HI designed the case. All authors have read and approved the final manuscript.
Supported by Biomedical Research Institute Grant from Pusan National University Hospital, No. 202500360001.
Institutional review board statement: This study was approved by the Pusan National University Hospital Institutional Review Board, No. 2503-019-149.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data that support the findings of this study are available from the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hyung Il Seo, MD, PhD, Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Yangsan 44955, South Korea. seohi71@hanmail.net
Received: June 7, 2025
Revised: July 21, 2025
Accepted: September 26, 2025
Published online: November 16, 2025
Processing time: 160 Days and 7.4 Hours
Core Tip

Core Tip: This study investigated the impact of obesity on the clinical characteristics and outcomes of patients undergoing elective laparoscopic cholecystectomy for gallstone disease. Obese patients showed distinct preoperative features, including higher American Society of Anesthesiologists scores, elevated glycated hemoglobin levels, and lower vitamin D levels; however, surgical outcomes were similar to those of non-obese patients. Postoperative care should focus on addressing obesity-related risks to improve long-term outcomes even when immediate surgical results are unaffected.