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Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2025; 13(31): 110734
Published online Nov 6, 2025. doi: 10.12998/wjcc.v13.i31.110734
Not losing sight of the bigger picture of complications associated with post-polypectomy syndrome: A case report and review of literature
Miguel Suárez, Raquel Martínez, Patricia C Santiago-Ramos
Miguel Suárez, Raquel Martínez, Department of Gastroenterology, Virgen de la Luz Hospital, Cuenca 16002, Castille-La Mancha, Spain
Miguel Suárez, Raquel Martínez, Medical Analysis Expert Group, Institute of Technology, Universidad de Castilla-La Mancha, Cuenca 16071, Castille-La Mancha, Spain
Miguel Suárez, Raquel Martínez, Medical Analysis Expert Group, Instituto de Investigación Sanitaria de Castilla-La Mancha, Toledo 45071, Castille-La Mancha, Spain
Patricia C Santiago-Ramos, Primary Care Center, Gerencia de Atención Integrada de Cuenca, Priego 16800, Castille-La Mancha, Spain
Author contributions: Suárez M, Martínez R, and Santiago-Ramos PC participated in the design, editing and data collection of the manuscript; Suárez M, Martínez R, and Santiago-Ramos PC contributed to the review of the literature and writing. All authors have reviewed and approved the paper.
Informed consent statement: Informed written consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: All authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Miguel Suárez, MD, PhD, Associate Chief Physician, Department of Gastroenterology, Virgen de la Luz Hospital, Hermandad Donantes De Sangre, Cuenca 16002, Castille-La Mancha, Spain. msuarezmatias@sescam.jccm.es
Received: June 13, 2025
Revised: July 9, 2025
Accepted: September 11, 2025
Published online: November 6, 2025
Processing time: 139 Days and 9.9 Hours
Core Tip

Core Tip: Although therapeutic colonoscopy is generally safe, it may be associated with significant complications. This case illustrates how post-polypectomy syndrome can mask a colonic perforation with subsequent abscess formation. It emphasizes the importance of an accurate initial endoscopic assessment, the use of advanced resection and closure techniques, and close clinical follow-up. Recognizing this spectrum of complications and intervening early can help prevent major surgical procedures and improve patient outcomes.