Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2025; 13(31): 109019
Published online Nov 6, 2025. doi: 10.12998/wjcc.v13.i31.109019
Published online Nov 6, 2025. doi: 10.12998/wjcc.v13.i31.109019
Applications and challenges of paclitaxel- coated balloons beyond coronary atherosclerotic heart disease
Yun Wang, Wen-Lan Fu, Yun-Long Zhou, Department of Oncology, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
De-Kui Gao, Department of Cardiology, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
Yin Tian, Department of Interventional Medicine, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
Li-Qiong She, Department of Critical Care Medicine, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
Gang Luo, Department of Pharmacy, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
A-Xiu Huang, Department of Laboratory Medicine, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
Co-first authors: Yun Wang and Yin Tian.
Author contributions: Gao DK directed the research, set the review's core theme, guided literature search, monitored writing, handled reviewers' feedback, and coordinated revisions, providing overall leadership; Wang Y managed comprehensive literature work, analyzed and integrated sources, structured the review, wrote the first draft, and finalized it through multiple revisions; Tian Y aided in literature search, focused on in - depth readings in specific fields, offered revision suggestions, and co - reviewed professional content with Gao DK for accuracy; She LQ and Fu WL facilitated manuscript discussions and coordinated among authors; Luo G specialized in molecular biological mechanisms, proofread the manuscript, and refined the language for better readability; Zhou YL helped with data collection, organization, and reference formatting; Huang AX ensured the manuscript conformed to the target journal's format requirements; All authors reviewed and approved the final version.
Supported by Mianyang Health Commission 2019 Scientific Research Encouragement Project, No. 201948.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: De-Kui Gao, Department of Cardiology, Jiangyou Second People's Hospital, No. 31 Juhui Road, Jiangyou 621701, Sichuan Province, China. 635651229@qq.com
Received: April 30, 2025
Revised: May 28, 2025
Accepted: September 4, 2025
Published online: November 6, 2025
Processing time: 185 Days and 16.1 Hours
Revised: May 28, 2025
Accepted: September 4, 2025
Published online: November 6, 2025
Processing time: 185 Days and 16.1 Hours
Core Tip
Core Tip: This review describes the applications of paclitaxel-coated balloons beyond coronary atherosclerotic diseases, including the practical experience and research achievements of drug-coated balloons in arterial diseases such as peripheral arteries, renal arteries, and intracranial arteries, as well as venous and vascular access, arterial inflammatory diseases, and non-vascular diseases. It also explores the molecular biological mechanisms of paclitaxel drug balloons under different anatomical characteristics, providing references for further clinical applications and research.