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World J Clin Cases. Aug 6, 2023; 11(22): 5193-5203
Published online Aug 6, 2023. doi: 10.12998/wjcc.v11.i22.5193
Research progress on reactive oxygen species production mechanisms in tumor sonodynamic therapy
He-Qin Dong, Xiao-Feng Fu, Min-Yan Wang, Jiang Zhu
He-Qin Dong, School of Medicine, Shaoxing University, Shaoxin 312000, Zhejiang Province, China
Xiao-Feng Fu, Min-Yan Wang, Jiang Zhu, Department of Ultrasound, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang Province, China
Author contributions: Dong HQ wrote the manuscript; Wang MY and Fu XF contributed equally to this work; Wang MY and Fu XF were mainly responsible for data collection and figure scheduling; Jiang Zhu were responsible for manuscript modification; all authors have read and approve the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82272004 and No. 81974470, and by the Nature Science Foundation of Zhejiang Province, No. LZ22H180001.
Conflict-of-interest statement: All the authors have no conflict-of-interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jiang Zhu, MD, PhD, Doctor, Professor, Department of Ultrasound, Women's Hospital, Zhejiang University School of Medicine, No. 1 Xueshi Road, Hangzhou 310000, Zhejiang Province, China. zhujiang1046@zju.edu.cn
Received: March 23, 2023
Peer-review started: March 23, 2023
First decision: April 19, 2023
Revised: April 27, 2023
Accepted: May 22, 2023
Article in press: May 22, 2023
Published online: August 6, 2023
Processing time: 133 Days and 3.7 Hours
Core Tip

Core Tip: This review mainly describes the mechanism of reactive oxygen species generation by sonodynamic therapy and enhances the efficiency of reactive oxygen species generation by improving hypoxia to increase the efficacy of sonodynamic therapy on tumor, and finally summarizes the clinical applications and prospects of sonodynamic therapy.