©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 6, 2022; 10(4): 1388-1393
Published online Feb 6, 2022. doi: 10.12998/wjcc.v10.i4.1388
Published online Feb 6, 2022. doi: 10.12998/wjcc.v10.i4.1388
Direct antiglobulin test-negative autoimmune hemolytic anemia in a patient with β-thalassemia minor during pregnancy: A case report
Yang Zhou, Yi-Ling Ding, Li-Juan Zhang, Mei Peng, Jian Huang, Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China
Author contributions: Zhou Y reviewed the literature and contributed to manuscript drafting; Ding YL and Peng M were responsible for making critical revisions related to important intellectual content of the manuscript; Zhang LJ and Huang J were the patient’s obstetricians, and responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Jian Huang, MD, PhD, Associate Professor, Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. huangjian2566@126.com
Received: September 4, 2021
Peer-review started: September 4, 2021
First decision: November 22, 2021
Revised: November 27, 2021
Accepted: December 25, 2021
Article in press: December 25, 2021
Published online: February 6, 2022
Processing time: 142 Days and 3.7 Hours
Peer-review started: September 4, 2021
First decision: November 22, 2021
Revised: November 27, 2021
Accepted: December 25, 2021
Article in press: December 25, 2021
Published online: February 6, 2022
Processing time: 142 Days and 3.7 Hours
Core Tip
Core Tip: Severe maternal anemia can cause serious adverse effects with a significant increase in maternal and neonatal mortality. We report the successful diagnosis and treatment of direct antiglobulin test test-negative autoimmune hemolytic anemia in a patient with β-thalassemia minor during pregnancy. The findings from this case report suggest that maternal anemia can have multiple etiologies, and blood transfusion is not always the appropriate treatment.