Yu SJ, Heo JH, Choi EJ, Kim JH, Lee HS, Kim SY, Lim JH. Role of multidetector computed tomography in patients with acute infectious colitis. World J Clin Cases 2022; 10(12): 3686-3697 [PMID: 35647171 DOI: 10.12998/wjcc.v10.i12.3686]
Corresponding Author of This Article
Hong Sub Lee, MD, PhD, Professor, Department of Internal Medicine, Inje University Busan Paik Hospital, 75 Bokji-ro, Busanjin-gu, Busan 47392, South Korea. hslee@paik.ac.kr
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Apr 26, 2022; 10(12): 3686-3697 Published online Apr 26, 2022. doi: 10.12998/wjcc.v10.i12.3686
Role of multidetector computed tomography in patients with acute infectious colitis
Seung Jung Yu, Jae Hyuk Heo, Eun Jeong Choi, Jong Hyuk Kim, Hong Sub Lee, Sun Young Kim, Jae Hoon Lim
Seung Jung Yu, Jae Hyuk Heo, Eun Jeong Choi, Hong Sub Lee, Department of Internal Medicine, Inje University Busan Paik Hospital, Busan 47392, South Korea
Jong Hyuk Kim, Jae Hoon Lim, Department of Radiology, Myongji Hospital, Hanyang University College of Medicine, Goyang 10475, South Korea
Sun Young Kim, Department of Cancer Control and Population Health, National Cancer Center, Goyang 10408, South Korea
Author contributions: Lee HS and Lim JH designed the research study; Lee HS, Yu SJ, Heo JH and Choi EJ performed the research; Kim SY contributed analytic tools; Yu SJ and Heo JH analyzed the data and wrote the manuscript; and All authors have read and approve the final manuscript.
Supported bythe 2019 Inje University research grant.
Institutional review board statement: Ethics committee approval was received for this study from Institutional Review Board of the Myongji hospital (Decision No. MJH 2018-08-020).
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at hslee@paik.ac.kr
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong Sub Lee, MD, PhD, Professor, Department of Internal Medicine, Inje University Busan Paik Hospital, 75 Bokji-ro, Busanjin-gu, Busan 47392, South Korea. hslee@paik.ac.kr
Received: May 31, 2021 Peer-review started: May 31, 2021 First decision: July 1, 2021 Revised: September 14, 2021 Accepted: March 4, 2022 Article in press: March 4, 2022 Published online: April 26, 2022 Processing time: 324 Days and 12.1 Hours
ARTICLE HIGHLIGHTS
Research background
Multidetector computed tomography (MDCT) findings are well known depending on the etiology of colitis such as ischemic colitis, infectious colitis, and pseudomembranous colitis, but comparison of MDCT findings between bactria and virus infection in infectious colitis has not been studied.
Research motivation
If we can better differentiate between bacterial colitis and viral colitis, we can get help in deciding on a treatment method, such as the use of antibiotics.
Research objectives
This study's objective is to examine the usefulness of MDCT in distinguishing the etiology of acute infectious colitis.
Research methods
The cause of infectious colitis was defined using stool polymerase chain reaction (PCR) test for 244 infectious colitis patients for 4 years, and CT findings according to the cause were compared by using 11 parameters.
Research results
The parameters of bacterial colitis, except for small bowel involvement and comb sign had a significantly higher odds ratio than parameters of viral coltitis.
Research conclusions
MDCT provides many clues that can be useful in suggesting a specific etiology of acute infectious colitis.
Research perspectives
This study had limitations such as retrospective study, selection bias and exception of other cause of colitis, so a large prospective and well-designed study, including protocols—such as MDCT, serology/bacteriology, and endoscopy result—is necessary.
