Sun LD, Chu X, Xu L, Fan XZ, Qian Y, Zuo DM. Primary intramedullary melanoma of lumbar spinal cord: A case report. World J Clin Cases 2021; 9(10): 2352-2356 [PMID: 33869613 DOI: 10.12998/wjcc.v9.i10.2352]
Corresponding Author of This Article
Yi Qian, MD, Associate Professor, The Fifth Affiliated Hospital, Southern Medical University, No. 566 Congcheng Avenue, Conghua District, Guangzhou 510900, Guangdong Province, China. 1328059119@qq.com
Research Domain of This Article
Neurosciences
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Apr 6, 2021; 9(10): 2352-2356 Published online Apr 6, 2021. doi: 10.12998/wjcc.v9.i10.2352
Primary intramedullary melanoma of lumbar spinal cord: A case report
Le-Dong Sun, Xin Chu, Li Xu, Xiu-Zhen Fan, Yi Qian, Da-Ming Zuo
Le-Dong Sun, Xin Chu, Li Xu, Xiu-Zhen Fan, Department of Dermatology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, Guangdong Province, China
Yi Qian, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou 510900, Guangdong Province, China
Da-Ming Zuo, Department of Medical Laboratory, Southern Medical University, Guangzhou 510515, Guangdong Province, China
Author contributions: Sun LD and Qian Y designed the study; Chu X helped prepare the radiology images; Xu L and Fan XZ analyzed the pathology images; Zuo DM wrote the manuscript; all authors read and approved the final manuscript.
Supported byFoundation of the President of the Fifth Affiliated Hospital, Southern Medical University, 2020.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to report.
CARE Checklist (2016) statement: We have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi Qian, MD, Associate Professor, The Fifth Affiliated Hospital, Southern Medical University, No. 566 Congcheng Avenue, Conghua District, Guangzhou 510900, Guangdong Province, China. 1328059119@qq.com
Received: November 25, 2020 Peer-review started: November 25, 2020 First decision: December 8, 2020 Revised: December 15, 2020 Accepted: December 28, 2020 Article in press: December 28, 2020 Published online: April 6, 2021 Processing time: 125 Days and 5 Hours
Abstract
BACKGROUND
Primary intramedullary melanoma is a very rare tumor, most frequently occurring in the cervical and thoracic spinal cord.
CASE SUMMARY
We present a rare case in which the primary intramedullary melanoma was located in the lumbar spine. A 56-year-old man complained of progressive intermittent pain in the lumbar area. Thoracic magnetic resonance imaging showed a spinal intramedullary tumor between the L3 and S1 levels. The tumor was resected entirely, and the diagnosis of malignant melanoma was confirmed by histopathology.
CONCLUSION
Primary melanoma of the spinal cord, particularly intramedullary localization, has rarely been reported in the previous literature. We describe a primary malignant melanoma of the lumbar spinal cord and discuss the challenges associated with the diagnosis.
