Pagani Junior MA, Siman Lopes L, Sergi Filho FA, Goes Scorsioni FA, Tavares Filho MB, Maluf Amaral RP, Medeiros LE, Guillen Carneiro LI, Belluzzo HG, Vinholo TR, Buchaim DV, Buchaim RL. Partial left hepatectomy in a young patient with ruptured hepatic adenoma: A case report. World J Clin Cases 2026; 14(2): 114671 [DOI: 10.12998/wjcc.v14.i2.114671]
Corresponding Author of This Article
Rogério Leone Buchaim, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, Quadra 9 - Jardim Brasil, Bauru - SP, Bauru 17012-901, São Paulo, Brazil. rogerio@fob.usp.br
Research Domain of This Article
Gastroenterology & Hepatology
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Case Report
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jan 16, 2026 (publication date) through Jan 23, 2026
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World Journal of Clinical Cases
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2307-8960
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Pagani Junior MA, Siman Lopes L, Sergi Filho FA, Goes Scorsioni FA, Tavares Filho MB, Maluf Amaral RP, Medeiros LE, Guillen Carneiro LI, Belluzzo HG, Vinholo TR, Buchaim DV, Buchaim RL. Partial left hepatectomy in a young patient with ruptured hepatic adenoma: A case report. World J Clin Cases 2026; 14(2): 114671 [DOI: 10.12998/wjcc.v14.i2.114671]
World J Clin Cases. Jan 16, 2026; 14(2): 114671 Published online Jan 16, 2026. doi: 10.12998/wjcc.v14.i2.114671
Partial left hepatectomy in a young patient with ruptured hepatic adenoma: A case report
Marcos Alberto Pagani Junior, Letícia Siman Lopes, Francisco Antonio Sergi Filho, Felippe Antonio Goes Scorsioni, Marcos Barbosa Tavares Filho, Raissa Poletto Maluf Amaral, Leonardo Escobar Medeiros, Lucca Idalgo Guillen Carneiro, Helena Gazini Belluzzo, Thais Rissato Vinholo, Daniela Vieira Buchaim, Rogério Leone Buchaim
Marcos Alberto Pagani Junior, Letícia Siman Lopes, Felippe Antonio Goes Scorsioni, Marcos Barbosa Tavares Filho, Raissa Poletto Maluf Amaral, Leonardo Escobar Medeiros, Lucca Idalgo Guillen Carneiro, Helena Gazini Belluzzo, Thais Rissato Vinholo, Department of Gastroenterology, University of Marília, Marilia 17525-160, São Paulo, Brazil
Francisco Antonio Sergi Filho, Department of Hepatobiliary Surgery and Liver Transplantation, Hospital do Coração (Hcor), São Paulo 04004-030, São Paulo, Brazil
Daniela Vieira Buchaim, Department of Anatomy, Medical School, University Center of Adamantina, Adamantina 17800-000, São Paulo, Brazil
Rogério Leone Buchaim, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, São Paulo, Brazil
Author contributions: Pagani Junior MA, Lopes LA, Sergi Filho FA, Góes Scorsioni FA, Tavares Filho MB contributed to manuscript writing and editing, and data collection; Maluf Amaral RP, Medeiros LE, Guillen Carneiro LI, Belluzzo HG, Vinholo TR contributed to data analysis; Buchaim DV, Buchaim RL contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rogério Leone Buchaim, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, Quadra 9 - Jardim Brasil, Bauru - SP, Bauru 17012-901, São Paulo, Brazil. rogerio@fob.usp.br
Received: September 26, 2025 Revised: November 1, 2025 Accepted: December 25, 2025 Published online: January 16, 2026 Processing time: 112 Days and 14.1 Hours
Abstract
BACKGROUND
Although hepatic adenomas (HA) account for less than 0.04% of all liver neoplasms, their occurrence in young women is rare but strongly associated with oral contraceptive use, particularly in the 20-40 years age group, with an annual incidence estimated at approximately 3 to 4 cases per 100000 population.
CASE SUMMARY
We report the case of a previously healthy 30-year-old female patient, a regular user of combined oral contraceptives, who presented with acute hemorrhagic abdomen due to spontaneous rupture of a HA. The clinical presentation occurred after physical exertion and was with evidence of intra-abdominal bleeding. Initial management included selective hepatic arterial embolization as a conservative approach. Due to ongoing hemorrhage, an urgent left partial hepatectomy was indicated.
CONCLUSION
The operation was completed without adverse events, and postoperative recovery was favorable. This report emphasizes the significance of prompt diagnosis and immediate surgical intervention when hemodynamic compromise occurs due to HA rupture.
Core Tip: Hepatic adenomas (HA) are rare benign liver neoplasms. Clinically, they are usually asymptomatic. We report a case of intra-abdominal hemorrhage due to spontaneous rupture, configuring a hemorrhagic acute abdomen with imminent risk to life. Combined with the analysis of cases indexed in PubMed, spontaneous rupture of a HA represents a rare and serious medical emergency, responsible for approximately 20%-30% of complications from these tumors. Early detection of suspicious lesions is a favorable factor for patient survival. After the discovery of HA, providing appropriate active treatment has positive effects on the prognosis of patients. The treatment plan should be based on the patient’s response to conservative measures and hepatic arterial embolization up to emergency hepatectomy, depending on the extent of the lesion and hemodynamic stability.
