Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5791
Revised: May 8, 2024
Accepted: June 24, 2024
Published online: September 6, 2024
Processing time: 99 Days and 15.3 Hours
Solitary fibrous tumor (SFT) is a remarkably uncommon mesenchymal tumor. STAT6 level and a combination of clinical, pathological, and molecular features are required to arrive at a proper diagnosis.
In this report, we present an intriguing case involving a 43-year-old woman who initially exhibited symptoms of a bleeding retroperitoneal tumor, initially resembling a gastrointestinal stromal tumor, but later confirmed as an SFT. However, a year later, what was initially believed to be a recurrence of her SFT was instead identified as a desmoid tumor.
Distinguishing SFT from other tumors was pivotal. Correcting misdiagnoses of tumor type initially and of recurrence later was necessary for appropriate treatment of the correct desmoid type.
Core Tip: A 43-year-old woman initially exhibited symptoms of a bleeding retroperitoneal tumor, resembling a gastrointestinal stromal tumor, but was later confirmed as a solitary fibrous tumor (SFT). However, a year later, what was initially believed to be a recurrence of her SFT was instead identified as a desmoid tumor. Asymptomatic and slow-growing, SFTs are frequently incidentally discovered during imaging. Accurate diagnosis plays an essential role in the effective treatment and management of SFT. The key initial step in this process is differentiating SFT from its sister tumors. Biological and antiangiogenic therapies hold potential as adjuncts to surgery in treating SFT.