Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2024; 12(25): 5791-5797
Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5791
Solitary fibrous tumor: A case report of this multifaceted tumor
Hani Maalouf, Ribal Aby Hadeer, Souad Ghattas, Omar Tabbikha, Hasan Numan, Raja Wakim
Hani Maalouf, Ribal Aby Hadeer, Souad Ghattas, Omar Tabbikha, Hasan Numan, Department of General Surgery, University of Balamand, Beirut 100, Lebanon
Raja Wakim, Department of General Surgery, Mount Lebanon Hospital University Medical Center, Beirut 7031, Lebanon
Co-first authors: Hani Maalouf and Ribal Aby Hadeer.
Author contributions: Maalouf H and Aby Hadeer R contributed to the manuscript writing, editing and data collection; Ghattas S, Tabbikha O, and Numan H contributed to data analysis; Wakim R contributed to the conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication and any accompanying images.
Conflict-of-interest statement: All authors report no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Souad Ghattas, MD, Doctor, Department of General Surgery, University of Balamand, Faculty of Medical Sciences, Beirut 100, Lebanon. souadnajibghattas@gmail.com
Received: April 8, 2024
Revised: May 8, 2024
Accepted: June 24, 2024
Published online: September 6, 2024
Processing time: 99 Days and 15.3 Hours
Abstract
BACKGROUND

Solitary fibrous tumor (SFT) is a remarkably uncommon mesenchymal tumor. STAT6 level and a combination of clinical, pathological, and molecular features are required to arrive at a proper diagnosis.

CASE SUMMARY

In this report, we present an intriguing case involving a 43-year-old woman who initially exhibited symptoms of a bleeding retroperitoneal tumor, initially resembling a gastrointestinal stromal tumor, but later confirmed as an SFT. However, a year later, what was initially believed to be a recurrence of her SFT was instead identified as a desmoid tumor.

CONCLUSION

Distinguishing SFT from other tumors was pivotal. Correcting misdiagnoses of tumor type initially and of recurrence later was necessary for appropriate treatment of the correct desmoid type.

Keywords: Solitary fibrous tumor; Retroperitoneal tumor; Soft tissue neoplasms; Sarcoma; NAB2-STAT6; Case report

Core Tip: A 43-year-old woman initially exhibited symptoms of a bleeding retroperitoneal tumor, resembling a gastrointestinal stromal tumor, but was later confirmed as a solitary fibrous tumor (SFT). However, a year later, what was initially believed to be a recurrence of her SFT was instead identified as a desmoid tumor. Asymptomatic and slow-growing, SFTs are frequently incidentally discovered during imaging. Accurate diagnosis plays an essential role in the effective treatment and management of SFT. The key initial step in this process is differentiating SFT from its sister tumors. Biological and antiangiogenic therapies hold potential as adjuncts to surgery in treating SFT.