Examining rhabdomyolysis-related acute kidney injury in COVID-19 patients and its comparison to other acute kidney injury types

doi:10.5501/wjv.v14.i2.100986

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Jun 25, 2025 (publication date) through Jun 23, 2025

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Virol. Jun 25, 2025; 14(2): 100986
Published online Jun 25, 2025. doi: 10.5501/wjv.v14.i2.100986

Examining rhabdomyolysis-related acute kidney injury in COVID-19 patients and its comparison to other acute kidney injury types

Liyan Ajit D Souza, Abdulqadir J Nashwan

Liyan Ajit D Souza, Research Intern, Hamad Medical Corporation, Doha 3050, Qatar

Abdulqadir J Nashwan, Nursing & Midwifery Research Department, Hamad Medical Corporation, Doha 3050, Qatar

Author contributions: D Souza LA and Nashwan AJ wrote the draft and critically reviewed the literature; and all authors have read and approved the final manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Abdulqadir J Nashwan, PhD, Nursing & Midwifery Research Department, Hamad Medical Corporation, Rayyan Road, Doha 3050, Qatar. anashwan@hamad.qa

Received: September 1, 2024
Revised: December 4, 2024
Accepted: December 27, 2024
Published online: June 25, 2025
Processing time: 295 Days and 1.8 Hours

Core Tip

Core Tip: The study explored differences between rhabdomyolysis (RM)-related acute kidney injury (AKI) and other AKI types in coronavirus disease 2019 (COVID-19) patients. RM patients had high inflammation, procalcitonin, C-reactive protein, and ferritin. The prognosis of RM-related AKI was considered worse in comparison to developing AKI from other causes in COVID-19 patients. RM is a risk factor for AKI in COVID-19 patients. Hence, follow-ups are essential to monitor RM development. Study limitations include small sample size, absence of kidney biopsies, and focus on the 1^st wave of the pandemic. Addressing these limitations leads to accurate result generation, potentially improving viral infection management for RM and AKI development.