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Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Oct 15, 2025; 17(10): 110302
Published online Oct 15, 2025. doi: 10.4251/wjgo.v17.i10.110302
Colorectal follicular lymphoma: A single-center retrospective study
Makoto Saito, Minoru Kanaya, Naoki Miyashita, Emi Yokoyama, Koh Izumiyama, Akio Mori, Masanobu Morioka, Takeshi Kondo
Makoto Saito, Minoru Kanaya, Naoki Miyashita, Emi Yokoyama, Koh Izumiyama, Akio Mori, Masanobu Morioka, Takeshi Kondo, Blood Disorders Center, Aiiku Hospital, Sapporo 064-0804, Hokkaido, Japan
Author contributions: Saito M designed this study and wrote the manuscript; Saito M, Kanaya M, Miyashita N, Yokoyama E, Izumiyama K, Mori A, Morioka M, Kondo T made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; All authors gave final approval of the version to be published and agree to be accountable for all aspects of the work.
Institutional review board statement: This study was conducted in accordance with the World Medical Association Declaration of Helsinki, and was approved by the Aiiku Hospital Clinical Research Review Board (No. 202505201).
Informed consent statement: All 5 patients provided written informed consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Makoto Saito, Chief Physician, Blood Disorders Center, Aiiku Hospital, Chuo-ku Minami 4 Nishi 25, Sapporo 064-0804, Hokkaido, Japan. ikyoku@aiiku-hp.or.jp
Received: June 4, 2025
Revised: June 11, 2025
Accepted: August 28, 2025
Published online: October 15, 2025
Processing time: 132 Days and 21.4 Hours
Core Tip

Core Tip: Follicular lymphoma (FL) occurring in the duodenum has already been established as a disease concept within the category of FL. In response to this, clinical characteristics of the colorectal FL, including its treatment and long-term outcome, are poorly understood owing to the rarity. This study aimed to clarify the characteristic clinical features of the colorectal FL. In the present study, colorectal FL progresses indolently, as with cases of nodal or duodenal lesions, and the overall survival was good because it was sensitive to chemotherapy with administration of bendamustine and rituximab even after the disease progressed without initial treatment.