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Contents Volume 17 Issue 7 July 26, 2025

Evidence Review

Childhood insulin resistance and neural stem cell dysfunction in psychiatric disorders: Role of de novo lipogenesis and treatment perspectives

Mohammad M Khan, Zaw Ali Khan, Mohsin Ali Khan, Gauri Pandey

World J Stem Cells 17(7):106194. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.106194

Abstract (166) | Core Tip (186) | Full Article (HTML) (588) | Figures (1-2) (187) | Tables (1-3) (169) | Full Article (PDF)-2067K (102) | Full Article with Cover (PDF)-2366K (105) | Full Article (XML)-397K (51) | Audio-1700K (10) | Received: 02/18/2025 | Revised: 04/20/2025 | Accepted: 06/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (10) | Timeline of Article Publication (1) | Cite | (50) | (47) | (0) | (0) | (0) | (6) | (1202) | Open

Review

Combining acupuncture and mesenchymal stem cell therapy offers promise as a treatment for inflammatory bowel disease

Wei-Gang Ma, Yu-Xin Si, Yong-Long Zhang, Wei-Fang Gao, Yu-Ge Dong, Yan-Qi Li, Zhi-Fang Xu, Qiang Xi, Zhong-Zheng Li

World J Stem Cells 17(7):105371. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.105371

Abstract (213) | Core Tip (218) | Full Article (HTML) (1451) | Figures (1-3) (159) | Tables (1-2) (216) | Full Article (PDF)-3638K (98) | Full Article with Cover (PDF)-3938K (179) | Full Article (XML)-320K (64) | Audio-765K (24) | Received: 01/19/2025 | Revised: 03/25/2025 | Accepted: 06/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (731) | Timeline of Article Publication (0) | Cite | (53) | (43) | (0) | (0) | (0) | (8) | (2167) | Open

Molecular and therapeutic effects of mesenchymal stem cell-derived exosomes on autoimmune diseases

Fatma Sengul Bag, Omer Faruk Bag

World J Stem Cells 17(7):107202. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.107202

Abstract (202) | Core Tip (190) | Full Article (HTML) (1948) | Figures (1-3) (154) | Tables (1-1) (232) | Full Article (PDF)-3003K (144) | Full Article with Cover (PDF)-3302K (125) | Full Article (XML)-268K (69) | Audio-414K (22) | Received: 03/17/2025 | Revised: 04/03/2025 | Accepted: 06/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (68) | Timeline of Article Publication (0) | Cite | (66) | (57) | (0) | (0) | (0) | (4) | (2672) | (2) | Open

Therapeutic strategies for intervertebral disc degeneration: Extracellular vesicles and microRNAs derived from mesenchymal stem cells

Young-Ju Lim, Min-Soo Seo, Sangbum Park, Gun Woo Lee

World J Stem Cells 17(7):107212. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.107212

Abstract (217) | Core Tip (190) | Full Article (HTML) (987) | Figures (1-2) (182) | Tables (1-2) (200) | Full Article (PDF)-3036K (91) | Full Article with Cover (PDF)-3335K (85) | Full Article (XML)-201K (50) | Audio-445K (6) | Received: 03/17/2025 | Revised: 04/15/2025 | Accepted: 06/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (143) | Timeline of Article Publication (0) | Cite | (56) | (51) | (0) | (0) | (0) | (1595) | (3) | Open

Nutrient sensing in intestinal stem cell: Linking dietary nutrients to cellular metabolic regulation

Wen-Hao Li, Xin-Yi Yuan, Zhe Wang, Rong Lin

World J Stem Cells 17(7):107770. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.107770

Abstract (177) | Core Tip (210) | Full Article (HTML) (1139) | Figures (1-3) (152) | Tables (1-1) (171) | Full Article (PDF)-1244K (128) | Full Article with Cover (PDF)-1544K (89) | Full Article (XML)-283K (57) | Audio-308K (8) | Received: 03/28/2025 | Revised: 05/06/2025 | Accepted: 07/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1) | Timeline of Article Publication (1) | Cite | (62) | (55) | (0) | (0) | (0) | (1736) | Open

Minireviews

Engineering the future of nanomedicine: Strategic approaches to extracellular vesicle-based drug administration regimens

Yuan-Long Ye, Lei Liu

World J Stem Cells 17(7):107080. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.107080

Abstract (183) | Core Tip (188) | Full Article (HTML) (825) | Figures (1-1) (182) | Tables (1-1) (187) | Full Article (PDF)-1866K (114) | Full Article with Cover (PDF)-2163K (89) | Full Article (XML)-223K (52) | Audio-732K (5) | Received: 03/14/2025 | Revised: 04/21/2025 | Accepted: 06/19/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (0) | Timeline of Article Publication (0) | Cite | (47) | (63) | (0) | (0) | (0) | (3) | (1449) | (4) | Open

When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients

Aisha Al-Battashy, Nouf Al-Farsi

World J Stem Cells 17(7):107153. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.107153

Abstract (197) | Core Tip (195) | Full Article (HTML) (733) | Figures (1-1) (170) | Tables (1-4) (178) | Full Article (PDF)-1614K (84) | Full Article with Cover (PDF)-1900K (63) | Full Article (XML)-212K (53) | Audio-706K (7) | Received: 03/16/2025 | Revised: 05/11/2025 | Accepted: 06/19/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (0) | Timeline of Article Publication (0) | Cite | (55) | (38) | (0) | (0) | (0) | (1281) | Open

Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential

Ye-Hua Li, Yi-Ning Yao, Shen-Ao Zhou, Yang Wang

World J Stem Cells 17(7):107688. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.107688

Abstract (190) | Core Tip (196) | Full Article (HTML) (941) | Figures (1-1) (165) | Tables (1-1) (189) | Full Article (PDF)-1797K (122) | Full Article with Cover (PDF)-2097K (75) | Full Article (XML)-161K (57) | Audio-280K (15) | Received: 03/27/2025 | Revised: 04/22/2025 | Accepted: 06/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (7) | Timeline of Article Publication (3) | Cite | (71) | (59) | (0) | (0) | (0) | (5) | (1549) | (4) | Open

Observational Study

Recombinant human thrombopoietin safety and efficacy in pediatric allogeneic hematopoietic stem cell transplantation: A cohort study

Xue-Guo Li, Ru-Min Wang, Wei Chen, Tong Yao, Fen Chen, Yan-Fang Xu, Tao Lang

World J Stem Cells 17(7):106579. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.106579

Abstract (201) | Core Tip (185) | Full Article (HTML) (713) | Figures (1-1) (145) | Tables (1-4) (165) | Full Article (PDF)-908K (99) | Full Article with Cover (PDF)-1208K (58) | Full Article (XML)-131K (54) | Audio-946K (12) | Received: 03/07/2025 | Revised: 04/15/2025 | Accepted: 06/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (6) | Timeline of Article Publication (0) | Cite | (51) | (42) | (0) | (0) | (0) | (3) | (1234) | (2) | Open

Basic Study

X inactive-specific transcript regulates mitochondrial function and neuronal differentiation of stem cells via IGF2BP2/CPT1A axis in models of spinal cord injury

Si-Xiang Zeng, Jin-Tao Ye, Si-Hua Huang, Ruo-Xi Liu

World J Stem Cells 17(7):101929. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.101929

Abstract (180) | Core Tip (179) | Full Article (HTML) (662) | Figures (1-7) (146) | Tables (1-1) (163) | Full Article (PDF)-1515K (78) | Full Article with Cover (PDF)-1814K (71) | Full Article (XML)-105K (71) | Audio-391K (19) | Received: 02/12/2025 | Revised: 03/07/2025 | Accepted: 06/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (33) | Timeline of Article Publication (0) | Cite | (42) | (48) | (0) | (0) | (0) | (1191) | (1) | Open

Differentiation of patient-specific induced pluripotent stem cells derived from type 1 diabetes peripheral blood mononuclear cells into pancreatic β-like cells

Kun Wang, Wei Lin, Jun-Yong Han, Jin-Yan Chen, Rong-Hua Liu, Zhen Yu, Jing-Jun Jin

World J Stem Cells 17(7):104607. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.104607

Abstract (204) | Core Tip (186) | Full Article (HTML) (1358) | Figures (1-4) (188) | Full Article (PDF)-8559K (154) | Full Article with Cover (PDF)-8857K (64) | Full Article (XML)-158K (60) | Audio-620K (25) | Supplementary Material-143K (56) | Received: 12/26/2024 | Revised: 03/26/2025 | Accepted: 06/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (120) | Timeline of Article Publication (0) | Cite | (52) | (47) | (0) | (0) | (0) | (5) | (1824) | (1) | Open

Systematic Reviews

Therapeutic potential of stem cell-derived exosomes in hair regeneration: A systematic review

Neil Poddar, Adarsh Aratikatla, Ashim Gupta

World J Stem Cells 17(7):108519. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.108519

Abstract (271) | Core Tip (197) | Full Article (HTML) (3950) | Figures (1-1) (138) | Tables (1-5) (486) | Full Article (PDF)-860K (162) | Full Article with Cover (PDF)-1159K (179) | Full Article (XML)-234K (78) | Audio-425K (19) | Received: 04/15/2025 | Revised: 05/27/2025 | Accepted: 06/16/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (62) | Timeline of Article Publication (0) | Cite | (63) | (57) | (0) | (0) | (0) | (4993) | (6) | Open

Meta-Analysis

Autologous and allogeneic mesenchymal stem cell-based therapies for diabetes mellitus: A systematic review and meta-analysis

Raisa A Aringazina, Afshin Zare, Seyyed Mojtaba Mousavi, Nurgul Abenova, Nadiar Maratovich Mussin, Amin Tamadon

World J Stem Cells 17(7):108202. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.108202

Abstract (215) | Core Tip (229) | Full Article (HTML) (1398) | Figures (1-6) (165) | Tables (1-3) (181) | Full Article (PDF)-8791K (192) | Full Article with Cover (PDF)-9091K (102) | Full Article (XML)-152K (56) | Audio-1133K (13) | Supplementary Material-529K (57) | Received: 04/07/2025 | Revised: 05/01/2025 | Accepted: 07/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (17) | Timeline of Article Publication (0) | Cite | (62) | (62) | (0) | (0) | (0) | (2094) | (2) | Open

Letter to the Editor

First-ever stem cell therapy restores insulin independence in type 1 diabetes: A medical milestone

Dinesh Kumar, Rajni Tanwar, Vrinda Gupta

World J Stem Cells 17(7):106856. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.106856

Abstract (1042) | Core Tip (244) | Full Article (HTML) (2908) | Tables (1-1) (239) | Full Article (PDF)-375K (194) | Full Article with Cover (PDF)-675K (87) | Full Article (XML)-48K (55) | Audio-2720K (33) | Received: 03/10/2025 | Revised: 05/14/2025 | Accepted: 06/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (362) | Timeline of Article Publication (0) | Cite | (49) | (54) | (0) | (0) | (0) | (5) | (3483) | (3) | Open

Long noncoding ribonucleic acid ENST00000517482 enhances mesenchymal stem cell therapy against acute lung injury

Yan Zhou, Bo-Tao Xu, Hai-Ying Zhou, Zhong-Tu Shang

World J Stem Cells 17(7):109064. Published online Jul 26, 2025. doi: 10.4252/wjsc.v17.i7.109064

Abstract (189) | Core Tip (181) | Full Article (HTML) (617) | Full Article (PDF)-353K (90) | Full Article with Cover (PDF)-655K (53) | Full Article (XML)-33K (51) | Audio-295K (17) | Received: 04/28/2025 | Revised: 05/17/2025 | Accepted: 07/01/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (35) | Timeline of Article Publication (0) | Cite | (51) | (52) | (0) | (0) | (0) | (4) | (811) | Open

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