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For: Pulido-Escribano V, Torrecillas-Baena B, Camacho-Cardenosa M, Dorado G, Gálvez-Moreno MÁ, Casado-Díaz A. Role of hypoxia preconditioning in therapeutic potential of mesenchymal stem-cell-derived extracellular vesicles. World J Stem Cells 2022; 14(7): 453-472 [PMID: 36157530 DOI: 10.4252/wjsc.v14.i7.453]
URL: https://www.wjgnet.com/1948-0210/full/v14/i7/453.htm
Number Citing Articles
1
Nhung Thi-Hong Dinh, Quyen Thi Nguyen, Ngo Thu Hang, Hong-Nhung Dao, Le Duc Son, Giang Trang Ngan, Can Van Mao, Xuan-Hai Do, Van T. Hoang, Liem Nguyen Thanh. Assessment of the safety of hypoxia-primed mesenchymal stem cells derived from umbilical cord and adipose tissues in animalsScientific Reports 2025; 15(1) doi: 10.1038/s41598-025-20018-5
2
Akinleye Stephen Akinrinde, Ekundayo Stephen Samuel, Bisi Olajumoke Adeoye. Dose-dependent effects of cobalt chloride supplementation in a rat model of acetic acid-induced ulcerative colitisComparative Clinical Pathology 2024; 33(5): 705 doi: 10.1007/s00580-024-03586-2
3
Xinling Luo, Weiqi Zeng, Erfeng Xiong, Ziming Wang, Jingsheng Huang, Meiqi Luo, Zhongxian He, Jinyu Liu, Dongdong Yuan. Hypoxia-preconditioning human bone marrow-derived mesenchymal stem cells induce high-quality mitochondrial transfer through gap junctions to alleviate ischemia-reperfusion injury in liver graftCell Communication and Signaling 2025; 23(1) doi: 10.1186/s12964-025-02497-1
4
Wei Bian, Xiangyu Zeng, Ziwen Liu, Mingyan Guan, Tegeleqi Bu, Haoze Li, Zewei Gao, Jianyu Liu. Hypoxia-conditioned BMSC exosomes improve short-term spinal cord injury outcomes via the miR-615-3p/PDE4C-mediated cAMP/PKA pathwayStem Cell Research & Therapy 2026;  doi: 10.1186/s13287-026-04895-9
5
Gordana Velikic, Gordana Supic, Dusica L. Maric, Miljan Puletic, Marija D. Maric, Branko Barac, Dusan M. Maric. Stem Cell and Exosome Therapy in Wound Healing: Traps, Paradoxes, and Tricks Transforming ParadigmsBiomedicines 2025; 13(12): 3030 doi: 10.3390/biomedicines13123030
6
Vitale Miceli, Giovanni Zito, Matteo Bulati, Alessia Gallo, Rosalia Busà, Gioacchin Iannolo, Pier Giulio Conaldi. Different priming strategies improve distinct therapeutic capabilities of mesenchymal stromal/stem cells: Potential implications for their clinical useWorld Journal of Stem Cells 2023; 15(5): 400-420 doi: 10.4252/wjsc.v15.i5.400
7
Cuc Huynh, Ngoc Vu, Trung Van, Phuc Pham. Effects of Exosomes From Hypoxia-Induced Adipose-Derived Stem Cells on Ameliorating PhotoagingClinical, Cosmetic and Investigational Dermatology 2025; : 1683 doi: 10.2147/CCID.S523936
8
Ayesha Nisar, Sawar Khan, Wen Li, Li Hu, Priyadarshani Nadeeshika Samarawickrama, Naheemat Modupeola Gold, Meiting Zi, Sardar Azhar Mehmood, Jiarong Miao, Yonghan He. Hypoxia and aging: molecular mechanisms, diseases, and therapeutic targetsMedComm 2024; 5(11) doi: 10.1002/mco2.786
9
Renata Trabach Santos, Cássia Lisboa Braga, Maria Eduarda de Sá Freire Onofre, Carla Medeiros da Silva, Nazareth de Novaes Rocha, Rodrigo Gonzaga Veras, Sabrina Sodré de Souza Serra, Douglas Esteves Teixeira, Sarah Aparecida dos Santos Alves, Beatriz Toja Miranda, Miria Gomes Pereira, Celso Caruso Neves, Monique Ramos de Oliveira Garcia, Christina Maeda Takiya, Patricia Rieken Macêdo Rocco, Fernanda Ferreira Cruz, Pedro Leme Silva. Cardioprotective effects of extracellular vesicles from hypoxia-preconditioned mesenchymal stromal cells in experimental pulmonary arterial hypertensionStem Cell Research & Therapy 2025; 16(1) doi: 10.1186/s13287-025-04604-y
10
Yasaman Nazerian, Amirhossein Nazerian, Fereshteh Mohamadi-Jahani, Parastoo Sodeifi, Maryam Jafarian, Seyed Amir Hossein Javadi. Hydrogel-encapsulated extracellular vesicles for the regeneration of spinal cord injuryFrontiers in Neuroscience 2023; 17 doi: 10.3389/fnins.2023.1309172
11
O. V. Zhidkova, E. R. Andreeva, L. B. Buravkova. Activated Endothelium Stimulates the Activity of Multipotent Mesenchymal Stromal Cells under Physiological Hypoxia or Short-Term Hypoxic Stress in vitroJournal of Evolutionary Biochemistry and Physiology 2024; 60(2): 690 doi: 10.1134/S0022093024020194
12
Alessia Dallatana, Linda Cremonesi, Francesco Pezzini, Gianluca Fontana, Giulio Innamorati, Luca Giacomello. The Placenta as a Source of Human Material for Neuronal RepairBiomedicines 2024; 12(7): 1567 doi: 10.3390/biomedicines12071567
13
Lijuan Zheng, Hui Gong, Jing Zhang, Linna Guo, Zhuofan Zhai, Shuang Xia, Zhiyu Hu, Jing Chang, Yizhu Jiang, Xinran Huang, Jingyi Ge, Bikui Zhang, Miao Yan. Strategies to improve the therapeutic efficacy of mesenchymal stem cell‐derived extracellular vesicle (MSC-EV): a promising cell-free therapy for liver diseaseFrontiers in Bioengineering and Biotechnology 2023; 11 doi: 10.3389/fbioe.2023.1322514
14
Vitale Miceli. Priming strategies to enhance the therapeutic efficacy of mesenchymal stromal/stem cell-derived vesicles in regenerative medicineExtracellular Vesicles and Circulating Nucleic Acids 2026; 7(1): 20 doi: 10.20517/evcna.2025.84
15
Su-Min Park, Yong-Hun Oh, Ga-Hyun Lim, Ga-Hee Yun, Kyung-Bo Kim, Ju-Hyun An, Kyung-Won Seo, Hwa-Young Youn. Deferoxamine preconditioning of canine stem cell derived extracellular vesicles alleviates inflammation in an EAE mouse model through STAT3 regulationScientific Reports 2024; 14(1) doi: 10.1038/s41598-024-68853-2
16
Eugenio Caradonna, Francesco Setacci, Jessica Lanza, Fulvio Ferrara, Carlo Setacci, Massimo Danese, Gaetano Lanza. Autologous Cell Therapy for Chronic Limb Threatening Ischemia: Towards Personalized MedicineAngiology 2025;  doi: 10.1177/00033197251376093
17
Siyi Xie, Meiling Liu, Yajie Kong, Yiming Yang, Ruixue Chen, Yuzhong Wang, Shuxing Cao, Yongzhou Song. Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitusFrontiers in Cell and Developmental Biology 2025; 13 doi: 10.3389/fcell.2025.1549096
18
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee. Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain InjuryAdvanced Science 2025; 12(44) doi: 10.1002/advs.202504147
19
M. I. Ezdakova, D. K. Matveeva, I. V. Andrianova, E. R. Andreeva. The Sensitivity of Multipotent Mesenchymal Stromal Cells to Short-Term Hypoxic Stress In Vitro Depends on the Efficiency of Homotypic Communication through Gap JunctionsMoscow University Biological Sciences Bulletin 2023; 78(3): 180 doi: 10.3103/S0096392523700086
20
Khawaja Husnain Haider. Priming mesenchymal stem cells to develop “super stem cells”World Journal of Stem Cells 2024; 16(6): 623-640 doi: 10.4252/wjsc.v16.i6.623
21
O. V. Zhidkova, E. R. Andreeva, L. B. Buravkova. Activated Endothelium Changes The Activity Of Multipotent Mesenchymal Stromal Cells During Physiological Hypoxia Or Short Hypoxic Stress In VitroРоссийский физиологический журнал им  И  М  Сеченова 2024; 110(3): 445 doi: 10.31857/S0869813924030086
22
Ziyang Ye, Wenjie Chen, Genpeng Li, Jing Huang, Jianyong Lei. Tissue-derived extracellular vesicles in cancer progression: mechanisms, roles, and potential applicationsCancer and Metastasis Reviews 2024; 43(2): 575 doi: 10.1007/s10555-023-10147-6
23
Nada Serhal, Bertrand Brassart, Lise Nannan, Sandra Audonnet, Christine Terryn, Gaël Poitevin, Pascale Cornillet‐Lefebvre, Florine Dubuisson, Hélène Peyret, Philippe Nguyen, Claire Tournois. Angiogenic Potential of Small Extracellular Vesicles Produced by Stimulated Mesenchymal Stromal Cells Under Hypoxic ConditionsJournal of Extracellular Biology 2026; 5(1) doi: 10.1002/jex2.70105
24
Magdalena Strecanska, Tatiana Sekelova, Maria Csobonyeiova, Lubos Danisovic, Michaela Cehakova. Therapeutic applications of mesenchymal/medicinal stem/signaling cells preconditioned with external factors: Are there more efficient approaches to utilize their regenerative potential?Life Sciences 2024; 346: 122647 doi: 10.1016/j.lfs.2024.122647
25
Sharif A. Sabe, Cynthia M. Xu, Brittany A. Potz, Akshay Malhotra, Mohamed Sabra, Dwight D. Harris, Mark Broadwin, M. Ruhul Abid, Frank W. Sellke. Comparative Analysis of Normoxia- and Hypoxia-Modified Extracellular Vesicle Therapy in Function, Perfusion, and Collateralization in Chronically Ischemic MyocardiumInternational Journal of Molecular Sciences 2023; 24(3): 2076 doi: 10.3390/ijms24032076
26
Narjes Seddighi, Mehdi Talebi, Karim Shamsasenjan, Mortaza Raeisi, AliAkbar Movassaghpour. Pro-tumorigenic effects and therapeutic implications of mesenchymal stem cell-derived exosomes under hypoxic conditions: a systematic reviewDiscover Oncology 2026;  doi: 10.1007/s12672-025-04279-0
27
Benshuai You, Chenglin Zhou, Yang Yang. MSC-EVs alleviate osteoarthritis by regulating microenvironmental cells in the articular cavity and maintaining cartilage matrix homeostasisAgeing Research Reviews 2023; 85: 101864 doi: 10.1016/j.arr.2023.101864
28
Silvia Peppicelli, Lido Calorini, Francesca Bianchini, Laura Papucci, Lucia Magnelli, Elena Andreucci. Acidity and hypoxia of tumor microenvironment, a positive interplay in extracellular vesicle release by tumor cellsCellular Oncology 2025; 48(1): 27 doi: 10.1007/s13402-024-00969-z
29
Marta Camacho-Cardenosa, Victoria Pulido-Escribano, Bárbara Torrecillas-Baena, Jose Manuel Quesada-Gómez, Aura D. Herrera-Martínez, Rafael R. Sola-Guirado, Gabriel Dorado, María Ángeles Gálvez-Moreno, Antonio Casado-Díaz. Combined Effects of Cyclic Hypoxic and Mechanical Stimuli on Human Bone Marrow Mesenchymal Stem Cell Differentiation: A New Approach to the Treatment of Bone LossJournal of Clinical Medicine 2024; 13(19): 5805 doi: 10.3390/jcm13195805
30
Victoria Pulido-Escribano, Marta Camacho-Cardenosa, Gabriel Dorado, José Manuel Quesada-Gómez, Alfonso Calañas-Continente, María Ángeles Gálvez-Moreno, Antonio Casado-Díaz. The Use of Plant-Derived Extracellular Vesicles in Regenerative Medicine Applied to Cutaneous Wound HealingPharmaceutics 2025; 17(12): 1531 doi: 10.3390/pharmaceutics17121531
31
Antonio Casado-Díaz. Stem Cells in Regenerative MedicineJournal of Clinical Medicine 2022; 11(18): 5460 doi: 10.3390/jcm11185460
32
Li Chen, Yang Yang, Junwei Chen, Yinghong Lin, Liang Xian, Yuhui Chen, Xingshu Zhu, Ying Tang, Yi Zuo, Shaohuai Xia, Xuewei Xia, Yongjun Xu, Shousen Wang. Intranasal delivery of hypoxia-preconditioned extracellular vesicles derived from BMSCs alleviates neuroinflammation and brain dysfunction in TBIStem Cell Research & Therapy 2025; 16(1) doi: 10.1186/s13287-025-04572-3
33
Dwight D. Harris, Sharif A. Sabe, Mark Broadwin, Christopher Stone, Cynthia Xu, Meghamsh Kanuparthy, Akshay Malhotra, M. Ruhul Abid, Frank W. Sellke. Intramyocardial injection of hypoxia-conditioned extracellular vesicles increases myocardial perfusion in a swine model of chronic coronary diseaseJTCVS Open 2024; 20: 49 doi: 10.1016/j.xjon.2024.06.003
34
Hon‐Lok Lo, Shih‐Hao Huang, Ting‐Hsuan Dai, Shun‐Cheng Wu, Cheng‐Jung Ho, Cheng‐Chang Lu. Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and ApoptosisThe Kaohsiung Journal of Medical Sciences 2026;  doi: 10.1002/kjm2.70176
35
Supeng Wang, Zhiqiang Jia, Minghai Dai, Xujun Feng, Chengxuan Tang, Liangle Liu, Lingling Cao. Advances in natural and synthetic macromolecules with stem cells and extracellular vesicles for orthopedic disease treatmentInternational Journal of Biological Macromolecules 2024; 268: 131874 doi: 10.1016/j.ijbiomac.2024.131874
36
Cássia Lisboa Braga, Renata Trabach Santos, Carla Medeiros da Silva, Nazareth de Novaes Rocha, Nathane Santanna Felix, Mayck Medeiros, Monique Martins Melo, Johnatas Dutra Silva, Douglas Esteves Teixeira, Celso Caruso Neves, Patricia Rieken Macedo Rocco, Fernanda Ferreira Cruz, Pedro Leme Silva. Therapeutic effects of hypoxia-preconditioned bone marrow-derived mesenchymal stromal cells and their extracellular vesicles in experimental pulmonary arterial hypertensionLife Sciences 2023; 329: 121988 doi: 10.1016/j.lfs.2023.121988
37
Wendy V. Jaraba-Álvarez, Ashanti C. Uscanga-Palomeque, Vanesa Sanchez-Giraldo, Claudia Madrid, Hector Ortega-Arellano, Karolynn Halpert, Carolina Quintero-Gil. Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factorsFrontiers in Cell and Developmental Biology 2025; 13 doi: 10.3389/fcell.2025.1609082
38
Wei Li, Xu Chen, Feng Zou, Xiaotong He. Extracellular Vesicles Derived From Hypoxia-Treated Human Adipose Stem Cells Increase Proliferation and Angiogenic Differentiation in Human Adipose Stem CellsAesthetic Surgery Journal 2023; 43(11): NP924 doi: 10.1093/asj/sjad139
39
Natalia Trufanova, Oleh Trufanov, Oleksandr Petrenko. Unlocking MSC Potential: Metabolic Reprogramming via Synthetic Biology ApproachesSynBio 2025; 3(3): 13 doi: 10.3390/synbio3030013
40
Mehdi Rasouli, Roya Fattahi, Ghader Nuoroozi, Zeinab Zarei-Behjani, Maliheh Yaghoobi, Zeinab Hajmohammadi, Simzar Hosseinzadeh. The role of oxygen tension in cell fate and regenerative medicine: implications of hypoxia/hyperoxia and free radicalsCell and Tissue Banking 2024; 25(1): 195 doi: 10.1007/s10561-023-10099-9
41
Jiawei Feng, Yichen Yao, Qixue Wang, Xiaozhou Han, Xiaofei Deng, Yemin Cao, Xinghua Chen, Mingmei Zhou, Cheng Zhao. Exosomes: Potential key players towards novel therapeutic options in diabetic woundsBiomedicine & Pharmacotherapy 2023; 166: 115297 doi: 10.1016/j.biopha.2023.115297
42
Gülsemin Çiçek, Fatma Bağcı, Mehmet Filizfidan, Selçuk Duman, Tahsin Aktan. Physicochemical and Biological Modifications in Mesenchymal Stem Cells-Derived Conditioned Media Under Hypoxic Preconditioning: Impact on Oxidative Stress and Nanoparticle StabilityLife 2025; 15(5): 702 doi: 10.3390/life15050702
43
Bogdan-Alexandru Hagiu. Can physical exercise and its mimetics enhance mitochondrial transfusion for Parkinson’s disease therapy?Medical Hypotheses 2025; 201: 111697 doi: 10.1016/j.mehy.2025.111697
44
Yi Liu, Ling Ren, Mengyao Li, Bowen Zheng, Yi Liu. The Effects of Hypoxia-Preconditioned Dental Stem Cell-Derived Secretome on Tissue RegenerationTissue Engineering Part B: Reviews 2025; 31(1): 44 doi: 10.1089/ten.teb.2024.0054
45
Marta Camacho-Cardenosa, Victoria Pulido-Escribano, Guadalupe Estrella-Guisado, Gabriel Dorado, Aura D. Herrera-Martínez, María Ángeles Gálvez-Moreno, Antonio Casado-Díaz. Bioprinted Hydrogels as Vehicles for the Application of Extracellular Vesicles in Regenerative MedicineGels 2025; 11(3): 191 doi: 10.3390/gels11030191
46
Dongdong Ti, Jun Yi, Huihua Chen, Haojie Hao, Chunmeng Shi. The Role of Mesenchymal Stem/Stromal Cells Secretome in Macrophage Polarization: Perspectives on Treating Inflammatory DiseasesCurrent Stem Cell Research & Therapy 2024; 19(6): 894 doi: 10.2174/1574888X18666230811093101
47
Özer Aylin Gurpinar, Irmak Dal. Treatment of Induced Mesenchymal Stem Cells in Ischemic Heart Diseases: HypoxiaHacettepe Journal of Biology and Chemistry 2025; 53(2): 49 doi: 10.15671/hjbc.1522356
48
Mohamed Sabra, Sharif A. Sabe, Dwight D. Harris, Cynthia M. Xu, Mark Broadwin, Krishnah G. Bellam, Debolina Banerjee, M. Ruhul Abid, Frank W. Sellke. Ischemic myocardial inflammatory signaling in starvation versus hypoxia-derived extracellular vesicles: A comparative analysisJTCVS Open 2023; 16: 419 doi: 10.1016/j.xjon.2023.10.004
49
Fanyi Zhao, Qixing Tang, Jie Liu. Functional impacts of lactylation in Hypoxia‒primed mesenchymal stromal cellsFrontiers in Cell and Developmental Biology 2025; 13 doi: 10.3389/fcell.2025.1678282
50
Jacob Raiten, Genevieve M. Abd, Shane B. Handelsman, Harshank V. Patel, Jennifer C. Ku, Agata M. Parsons, Jonathan L. Wassink, Sheridan L. Hayes, Juliana Overbay, Yong Li. Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejectionFrontiers in Pharmacology 2024; 15 doi: 10.3389/fphar.2024.1471563
51
Anne Kari Smedås, Lovise Gangeskar Paris, Niyaz Al‐Sharabi, Einar K. Kristoffersen, Mariano Sanz, Kamal Mustafa, Dagmar Fosså Bunæs, Siddharth Shanbhag. Secretomes of Gingival Fibroblasts From Periodontally Diseased Tissues: A Proteomic AnalysisClinical and Experimental Dental Research 2025; 11(1) doi: 10.1002/cre2.70103
52
Bárbara Torrecillas-Baena, Victoria Pulido-Escribano, Gabriel Dorado, María Ángeles Gálvez-Moreno, Marta Camacho-Cardenosa, Antonio Casado-Díaz. Clinical Potential of Mesenchymal Stem Cell-Derived Exosomes in Bone RegenerationJournal of Clinical Medicine 2023; 12(13): 4385 doi: 10.3390/jcm12134385
53
Vincent S Gallicchio. Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-IJournal of Regenerative Medicine & Biology Research 2024; : 1 doi: 10.46889/JRMBR.2024.5202
54
Cathal Patrick Forkan, Aruna Shrestha, Alfred Yu, Christine Chuang, Flemming Pociot, Reza Yarani. Could hypoxic conditioning augment the potential of mesenchymal stromal cell-derived extracellular vesicles as a treatment for type 1 diabetes?Stem Cell Research & Therapy 2025; 16(1) doi: 10.1186/s13287-025-04153-4
55
Chendong Peng, Jie Yan, Yu’ang Jiang, Lin Wu, Miaoling Li, Xinrong Fan. Exploring Cutting-Edge Approaches to Potentiate Mesenchymal Stem Cell and Exosome Therapy for Myocardial InfarctionJournal of Cardiovascular Translational Research 2024; 17(2): 356 doi: 10.1007/s12265-023-10438-x
56
Dwight D. Harris, Sharif A. Sabe, Mark Broadwin, Cynthia Xu, Christopher Stone, Meghamsh Kanuparthy, Akshay Malhotra, M. Ruhul Abid, Frank W. Sellke. Intramyocardial Injection of Hypoxia-Conditioned Extracellular Vesicles Modulates Response to Oxidative Stress in the Chronically Ischemic MyocardiumBioengineering 2024; 11(2): 125 doi: 10.3390/bioengineering11020125
57
María Ángeles de Pedro, Esther López, Francisco Manuel González-Nuño, María Pulido, Verónica Álvarez, Ana María Marchena, Christian Preußer, Witold Szymański, Elke Pogge von Strandmann, Johannes Graumann, Francisco Miguel Sánchez-Margallo, Javier G. Casado, María Gómez-Serrano. Menstrual blood-derived mesenchymal stromal cells: impact of preconditioning on the cargo of extracellular vesicles as potential therapeuticsStem Cell Research & Therapy 2023; 14(1) doi: 10.1186/s13287-023-03413-5
58
Yi Tian, Xiancheng Wang, Yang Sun, Xiang Xiong, Weiliang Zeng, Kai Yang, Hongli Zhao, Yiwen Deng, Dandan Song. NPTX1 Mediates the Facilitating Effects of Hypoxia-Stimulated Human Adipocytes on Adipose-Derived Stem Cell Activation and Autologous Adipose Graft Survival RateAesthetic Plastic Surgery 2024; 48(20): 4203 doi: 10.1007/s00266-024-04118-7
59
Bastien Thauvin, Eric Olmos, Elise Madec, Camille Simon, Julien Branchu, Latifa Chebil. Bead to Bead Transfer, an Efficient Strategy to Scale‐up the Mesenchymal Stromal Cells‐Derived Secretome BioproductionBiotechnology and Bioengineering 2025; 122(11): 3037 doi: 10.1002/bit.70042
60
M.I. Ezdakova, D.K. Matveeva, I.V. Andrianova, E.R. Andreeva. The sensitivity of multipotent mesenchymal stromal cells to short-term hypoxic stress in vitro depends on the efficiency of homotypic communication through gap junctionsVestnik Moskovskogo universiteta. Seria 16. Biologia 2023; 78(№3, 2023): 195 doi: 10.55959/MSU0137-0952-16-78-3-7
61
Kevin Audoux, Elise Madec, Julien Branchu, Eric Olmos, Jessica Schiavi-Tritz. Influence of oxygen conditioning on the production of secretome by human mesenchymal stromal cells in stirred bioreactorsCytotherapy 2026; 28(2): 102003 doi: 10.1016/j.jcyt.2025.102003
62
Junyan Zhu, Sicong Wang, Dakai Yang, Wenrong Xu, Hui Qian. Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseasesJournal of Nanobiotechnology 2023; 21(1) doi: 10.1186/s12951-023-01921-3
63
Jiantao Wang, Jianxin Cui, Shengqiang Yu, Shujie Xia. Mesenchymal stem cell‐derived extracellular vesicles in treatment against renal fibrosisClinical and Translational Discovery 2023; 3(5) doi: 10.1002/ctd2.211
64
Michael Keese, Jiaxing Zheng, Kaixuan Yan, Karen Bieback, Benito A. Yard, Prama Pallavi, Christoph Reissfelder, Mark Andreas Kluth, Martin Sigl, Vugar Yugublu. Adipose-Derived Mesenchymal Stem Cells Protect Endothelial Cells from Hypoxic Injury by Suppressing Terminal UPR In Vivo and In VitroInternational Journal of Molecular Sciences 2023; 24(24): 17197 doi: 10.3390/ijms242417197
65
Zixuan Sun, Jiali Li, Zhijing Wu, Jiaxin Zhang, Tangrong Wang, Yuzhou Zheng, XueZhong Xu, Wei Ding, Hui Qian, Yulin Tan. Extracellular vesicles and their mimetics: clinical application prospects in medical aestheticsBurns & Trauma 2025; 13 doi: 10.1093/burnst/tkaf033
66
Mefina Kuntjoro, Nike Hendrijantini, Eric Priyo Prasetyo, Bambang Agustono, Guang Hong. Hypoxia-Preconditioned Human Umbilical Cord Mesenchymal Stem Cells Transplantation Ameliorates Inflammation and Bone Regeneration in Peri-Implantitis Rat ModelEuropean Journal of Dentistry 2025; 19(02): 420 doi: 10.1055/s-0044-1791530
67
Dwight D. Harris, Sharif A. Sabe, Mohamed Sabra, Cynthia M. Xu, Akshay Malhotra, Mark Broadwin, Debolina Banerjee, M. Ruhul Abid, Frank W. Sellke. Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardiumJTCVS Open 2023; 15: 220 doi: 10.1016/j.xjon.2023.05.013
68
Carolina Quintero-Gil, Wendy Jaraba-Alvarez, Juan P Franco-Salazar, Yurany Blanquiceth, Ferley A Bedoya-Guzmán, Sofía Ortiz-Tamayo, Natalia Quiroz-Correa, Vanesa Sanchez-Giraldo, Karolynn Halpert, Héctor Ortega-Arellano. Cryopreserved exosomes derived from hypoxic Wharton’s jelly mesenchymal stromal cells enhance fibroblast proliferation, upregulate COL1A2 expression, and mitigate senescenceFrontiers in Medicine 2025; 12 doi: 10.3389/fmed.2025.1692585
69
Ilias Nikolits, Farhad Chariyev-Prinz, Dominik Egger, Falk Liebner, Nicolas Mytzka, Cornelia Kasper. Characterization of MSC Growth, Differentiation, and EV Production in CNF Hydrogels Under Static and Dynamic Cultures in Hypoxic and Normoxic ConditionsBioengineering 2024; 11(10): 1050 doi: 10.3390/bioengineering11101050
70
Carolina Jiménez-Navarro, Bárbara Torrecillas-Baena, Marta Camacho-Cardenosa, José Manuel Quesada-Gómez, María Ángeles Gálvez-Moreno, Antonio Casado-Díaz. Effect of extracellular vesicles derived from hypoxia-preconditioned human mesenchymal stem cells on osteoblastogenesis and adipogenesis in vitroRevista de Osteoporosis y Metabolismo Mineral 2023;  doi: 10.20960/RevOsteoporosMetabMiner.00012
71
Jiawei Song, Mengmeng Hou, Yajie Guo, Han Peng, Shuai Liu, Jun Zhu, Qi Wang, Jipeng Li, Chenggang Yi, Huichen Li. Hypoxia-Preconditioned Adipose Stem Cell Exosomes Promote Adipose Graft Vascular Regeneration via miRNA-126Aesthetic Plastic Surgery 2025; 49(9): 2588 doi: 10.1007/s00266-024-04645-3
72
Shalmali Pendse, Vaijayanti Kale, Anuradha Vaidya. Microvesicles secreted by CoCl2-primed mesenchymal stromal cells boost the functionality of hematopoietic stem cells cultured with themAnnals of Hematology 2025; 104(10): 5389 doi: 10.1007/s00277-025-06652-z
73
Yihan Chen, Mingxin Hu, Yan Lam Lee, Leyi Chen, Shulan Lin, Xin Li, Jianguang Xu, Chengfei Zhang. Progress and Perspectives in Allogeneic Cell‐Based Pulp RegenerationInternational Endodontic Journal 2025;  doi: 10.1111/iej.70080
74
Mohammad Amin Khalilzad, Javad Mohammadi, Soumayeh Amirsaadat, Sajad Najafi, Sona Zare, Mohammad Ali Nilforoushzadeh, Mitra Khalilzad, Mohammad Amir Amirkhani, Aysan Peyrovan, Seyedeh Fatemeh Sadati Khalili, Atefeh Farahani, Solmaz Zare. Therapeutic potential of apoptotic vesicles in modulating inflammation, immune responses, and tissue regenerationJournal of Nanobiotechnology 2025; 23(1) doi: 10.1186/s12951-025-03278-1
75
Johannes Burtscher, Tom Citherlet, Alba Camacho‐Cardenosa, Marta Camacho‐Cardenosa, Antoine Raberin, Bastien Krumm, Erich Hohenauer, Margit Egg, Mona Lichtblau, Julian Müller, Elena A. Rybnikova, Hannes Gatterer, Tadej Debevec, Sebastien Baillieul, Giorgio Manferdelli, Tom Behrendt, Lutz Schega, Hannelore Ehrenreich, Grégoire P. Millet, Max Gassmann, Christoph Schwarzer, Oleg Glazachev, Olivier Girard, Sophie Lalande, Michael Hamlin, Michele Samaja, Katharina Hüfner, Martin Burtscher, Gino Panza, Robert T. Mallet. Mechanisms underlying the health benefits of intermittent hypoxia conditioningThe Journal of Physiology 2024; 602(21): 5757 doi: 10.1113/JP285230
76
Xinling Zhang, Yuhang Zhang, Xirui Peng, Luxiang Yang, Jingwen Miao, Yuyang Yue, Yong Wang, Xiaoyang Wang, Changlian Zhu, Juan Song. Targeting Neuroinflammation in Preterm White Matter Injury: Therapeutic Potential of Mesenchymal Stem Cell-Derived ExosomesCellular and Molecular Neurobiology 2025; 45(1) doi: 10.1007/s10571-025-01540-6
77
David A. Hart. Use of Brain-Derived Stem/Progenitor Cells and Derived Extracellular Vesicles to Repair Damaged Neural Tissues: Lessons Learned from Connective Tissue Repair Regarding Variables Limiting Progress and Approaches to Overcome LimitationsInternational Journal of Molecular Sciences 2023; 24(4): 3370 doi: 10.3390/ijms24043370