BPG is committed to discovery and dissemination of knowledge
Home / Archive / Volume 12, Issue 12
This Article
Academic Content and Language Evaluation of This Article
CrossCheck and Google Search of This Article
Academic Rules and Norms of This Article
Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Number of Hits and Downloads for This Article
  • Total Article Views (13815)
All Articles published online
The chart showing PDF series, WORD series, HTML series, Figures (1-1) series, Tables (1-1) series.
Item 
Count 
PDF846
WORD169
HTML9436
Figures (1-1)505
Tables (1-1)448
 Sum=11404
Publishing Process of This Article
The chart showing Browse series, Download series.
Item 
Count 
Browse715
Download1696
 Sum=2411
Dec 26, 2020 (publication date) through Apr 6, 2025
Times Cited of This Article
Journal Information of This Article
Publication Name
World Journal of Stem Cells
ISSN
1948-0210
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Cited by in CrossRef
For: González-González A, García-Sánchez D, Dotta M, Rodríguez-Rey JC, Pérez-Campo FM. Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine. World J Stem Cells 2020; 12(12): 1529-1552 [PMID: 33505599 DOI: 10.4252/wjsc.v12.i12.1529]
URL: https://www.wjgnet.com/1948-0210/full/v12/i12/1529.htm
Number Citing Articles
1
Başak Işıldar, Serbay Özkan, Meral Koyutürk. Preconditioning of Human Umbilical Cord Mesenchymal Stem Cells with a Histone Deacetylase Inhibitor: Valproic Acid. Balkan Medical Journal 2024; : 369 doi: 10.4274/balkanmedj.galenos.2024.2024-6-25
2
Alessandra Camarca, Vera Rotondi Aufiero, Giuseppe Mazzarella. Role of Regulatory T Cells and Their Potential Therapeutic Applications in Celiac Disease. International Journal of Molecular Sciences 2023; 24(19): 14434 doi: 10.3390/ijms241914434
3
Javiera Gallardo, Pablo Berríos-Cárcamo, Fernando Ezquer. Advances in Alcohol Use Disorder Treatment. International Review of Neurobiology 2024; 178: 179 doi: 10.1016/bs.irn.2024.07.002
4
Jack Gemayel, Diana Chaker, Georges El Hachem, Melissa Mhanna, Rawad Salemeh, Colette Hanna, Frederic Harb, Ahmad Ibrahim, Alain Chebly, Charbel Khalil. Mesenchymal stem cells-derived secretome and extracellular vesicles: perspective and challenges in cancer therapy and clinical applications. Clinical and Translational Oncology 2023; 25(7): 2056 doi: 10.1007/s12094-023-03115-7
5
Vitalii Moskalov, Olena Koshova, Sabina Ali, Nataliia Filimonova, Irina Tishchenko. Impact of xenogenic mesenchimal stem cells secretome on a humoral component of the immune system. WikiJournal of Medicine 2023; 10(1): X doi: 10.15347/wjm/2023.004
6
Shuangpeng Jiang, Guangzhao Tian, Xu Li, Zhen Yang, Fuxin Wang, Zhuang Tian, Bo Huang, Fu Wei, Kangkang Zha, Zhiqiang Sun, Xiang Sui, Shuyun Liu, Weimin Guo, Quanyi Guo, Liang Gao. Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration. Stem Cells International 2021; 2021: 1 doi: 10.1155/2021/8882505
7
Hai Hu, Yuesong Yin, Hecheng Zhou, Binbin Jiang, Ting Cai, Song Wu, Shuangfei Guo. Umbilical cord mesenchymal stem cell-derived exosomal Follistatin inhibits fibrosis and promotes muscle regeneration in mice by influencing Smad2 and AKT signaling. Experimental Cell Research 2025; 444(2): 114396 doi: 10.1016/j.yexcr.2024.114396
8
Basak Isildar, Serbay Ozkan, Merve Ercin, Selda Gezginci-Oktayoglu, Mahmut Oncul, Meral Koyuturk. 2D and 3D cultured human umbilical cord-derived mesenchymal stem cell-conditioned medium has a dual effect in type 1 diabetes model in rats: immunomodulation and beta-cell regeneration. Inflammation and Regeneration 2022; 42(1) doi: 10.1186/s41232-022-00241-7
9
Elissa Elia, David Brownell, Stéphane Chabaud, Stéphane Bolduc. Tissue Engineering for Gastrointestinal and Genitourinary Tracts. International Journal of Molecular Sciences 2022; 24(1): 9 doi: 10.3390/ijms24010009
10
Joseph P. Flemming, Peter J. Wermuth, Mỹ G. Mahoney. Extracellular Vesicles in the Skin Microenvironment: Emerging Roles as Biomarkers and Therapeutic Tools in Dermatologic Health and Disease. Journal of Investigative Dermatology 2024; 144(2): 225 doi: 10.1016/j.jid.2023.08.024
11
Györgyi Műzes, Ferenc Sipos. Mesenchymal Stem Cell-Derived Secretome: A Potential Therapeutic Option for Autoimmune and Immune-Mediated Inflammatory Diseases. Cells 2022; 11(15): 2300 doi: 10.3390/cells11152300
12
Katherine Miclau, William S. Hambright, Johnny Huard, Martin J. Stoddart, Chelsea S. Bahney. Cellular expansion of MSCs: Shifting the regenerative potential. Aging Cell 2023; 22(1) doi: 10.1111/acel.13759
13
XIAOXU ZHANG, LIN ZHANG, LIN DU, HUIYAN SUN, XIA ZHAO, YANG SUN, WEI WANG, LISHENG WANG. The antioxidant trolox inhibits aging and enhances prostaglandin E-2 secretion in mesenchymal stem cells. BIOCELL 2023; 47(2): 385 doi: 10.32604/biocell.2023.025203
14
Márcia Bastos Convento, Andreia Silva de Oliveira, Mirian Aparecida Boim, Fernanda Teixeira Borges. Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles as Natural Nanocarriers in the Treatment of Nephrotoxic Injury In Vitro. Cells 2024; 13(19): 1658 doi: 10.3390/cells13191658
15
Hanife Nurdan Olcar, Basak Isildar, Serbay Ozkan, Merve Ercin, Selda Gezginci‐Oktayoglu, Meral Koyuturk. Investigation of conditioned medium properties obtained from human umbilical cord mesenchymal stem/stromal cells preconditioned with dimethyloxalylglycine in a correlation with ultrastructural changes. Microscopy Research and Technique 2024; 87(1): 159 doi: 10.1002/jemt.24420
16
Enrico Ragni, Carlotta Perucca Orfei, Federico Valli, Luigi Zagra, Laura de Girolamo. Molecular Characterization of Secreted Factors and Extracellular Vesicles-Embedded miRNAs from Bone Marrow-Derived Mesenchymal Stromal Cells in Presence of Synovial Fluid from Osteoarthritis Patients. Biology 2022; 11(11): 1632 doi: 10.3390/biology11111632
17
Alejandro Casado-Santos, Elsa González-Cubero, Mª. Belén García-Rodríguez, Álvaro Carrera-Serna, Mª Luisa González-Fernández, Vega Villar-Suárez. The therapeutic potential of mesenchymal stromal cell secretome in treating spontaneous chronic corneal epithelial defects in dogs. Research in Veterinary Science 2025; 185: 105559 doi: 10.1016/j.rvsc.2025.105559
18
Inês Leal Reis, Bruna Lopes, Patrícia Sousa, Ana Catarina Sousa, Mariana Branquinho, Ana Rita Caseiro, Sílvia Santos Pedrosa, Alexandra Rêma, Cláudia Oliveira, Beatriz Porto, Luís Atayde, Irina Amorim, Rui Alvites, Jorge Miguel Santos, Ana Colette Maurício. Allogenic Synovia-Derived Mesenchymal Stem Cells for Treatment of Equine Tendinopathies and Desmopathies—Proof of Concept. Animals 2023; 13(8): 1312 doi: 10.3390/ani13081312
19
Akram Hoseinzadeh, Zahra Rezaieyazdi, Mahmoud Mahmoudi, Jalil Tavakol Afshari, Fahimeh Lavi Arab, Seyed-Alireza Esmaeili, Arezoo Faridzadeh, Amin Rezaeian, Sara Hoseini, Mehdi Barati, Ali Mahmoudi, Nafiseh Sadat Tabasi. Dysregulated balance in Th17/Treg axis of Pristane-induced lupus mouse model, are mesenchymal stem cells therapeutic?. International Immunopharmacology 2023; 117: 109699 doi: 10.1016/j.intimp.2023.109699
20
Joo Hee Choi, Soo In Kim, Jin Sol Seo, Normin-Erdene Tumursukh, Se Eun Kim, Seung Ho Choe, Seung Jae Kim, Sunjae Park, Jeong Eun Song, Gilson Khang. Fast stress relaxing gellan gum that enhances the microenvironment and secreting function of bone mesenchymal stem cells. International Journal of Biological Macromolecules 2022; 222: 2144 doi: 10.1016/j.ijbiomac.2022.10.011
21
Fatemeh Ahmadpour, Afrooz Karimi, Mohammd mahdi Saadatmandfar, Samaneh Karimi. Suppressing Effect of Human Wharton’s Jelly Mesenchymal Stem Cell Secretomes on Oxidative Stress Induced by Breast Cancer Cell Line SK-BR3. Jentashapir Journal of Cellular and Molecular Biology 2023; 14(4) doi: 10.5812/jjcmb-141019
22
Agnese Gugliandolo, Emanuela Mazzon. Dental Mesenchymal Stem Cell Secretome: An Intriguing Approach for Neuroprotection and Neuroregeneration. International Journal of Molecular Sciences 2021; 23(1): 456 doi: 10.3390/ijms23010456
23
Maria G. Savvidou, Ioulia Georgiopoulou, Nasia Antoniou, Soultana Tzima, Maria Kontou, Vasiliki Louli, Chronis Fatouros, Kostis Magoulas, Fragiskos N. Kolisis. Extracts from Chlorella vulgaris Protect Mesenchymal Stromal Cells from Oxidative Stress Induced by Hydrogen Peroxide. Plants 2023; 12(2): 361 doi: 10.3390/plants12020361
24
Giusi Alberti, Eleonora Russo, Simona Corrao, Rita Anzalone, Peter Kruzliak, Vitale Miceli, Pier Giulio Conaldi, Francesca Di Gaudio, Giampiero La Rocca. Current Perspectives on Adult Mesenchymal Stromal Cell-Derived Extracellular Vesicles: Biological Features and Clinical Indications. Biomedicines 2022; 10(11): 2822 doi: 10.3390/biomedicines10112822
25
Forough Mahdavi-Jouibari, Benyamin Parseh, Ezatolah Kazeminejad, Ayyoob Khosravi. Hopes and opportunities of stem cells from human exfoliated deciduous teeth (SHED) in cartilage tissue regeneration. Frontiers in Bioengineering and Biotechnology 2023; 11 doi: 10.3389/fbioe.2023.1021024
26
Kate Da Silva, Pradeep Kumar, Yahya E. Choonara. The paradigm of stem cell secretome in tissue repair and regeneration: Present and future perspectives. Wound Repair and Regeneration 2025; 33(1) doi: 10.1111/wrr.13251
27
Phillip Blondeel. The perpetual changing paradigm in reconstructive surgery: Developing a vision for the future. Journal of Plastic, Reconstructive & Aesthetic Surgery 2023; 77: 179 doi: 10.1016/j.bjps.2022.10.038
28
Fatema Tuz Zohora, Mansur Aliyu, Ali Akbar Saboor-Yaraghi. Secretome-based acellular therapy of bone marrow-derived mesenchymal stem cells in degenerative and immunological disorders: A narrative review. Heliyon 2023; 9(7): e18120 doi: 10.1016/j.heliyon.2023.e18120
29
Juan Carlos Chachques, Chiara Gardin, Nermine Lila, Letizia Ferroni, Veronique Migonney, Celine Falentin-Daudre, Federica Zanotti, Martina Trentini, Giulia Brunello, Tiberio Rocca, Vincenzo Gasbarro, Barbara Zavan. Elastomeric Cardiowrap Scaffolds Functionalized with Mesenchymal Stem Cells-Derived Exosomes Induce a Positive Modulation in the Inflammatory and Wound Healing Response of Mesenchymal Stem Cell and Macrophage. Biomedicines 2021; 9(7): 824 doi: 10.3390/biomedicines9070824
30
Bruna Lopes, Patrícia Sousa, Rui Alvites, Mariana Branquinho, Ana Catarina Sousa, Carla Mendonça, Luís Miguel Atayde, Ana Lúcia Luís, Artur S. P. Varejão, Ana Colette Maurício. Peripheral Nerve Injury Treatments and Advances: One Health Perspective. International Journal of Molecular Sciences 2022; 23(2): 918 doi: 10.3390/ijms23020918
31
Dazhi Yang, Zecai Chen, Zhen Xu, Lei Qin, Weihong Yi, Yufeng Long. Roles of Stem Cell Exosomes and their MicroRNA Carrier in Bone and Cartilage Regeneration. Current Stem Cell Research & Therapy 2023; 18(7): 917 doi: 10.2174/1574888X17666220817093305
32
Mahmoud Kandeel, Mohamed A. Morsy, Khalid M. Alkhodair, Sameer Alhojaily. Mesenchymal Stem Cell-Derived Extracellular Vesicles: An Emerging Diagnostic and Therapeutic Biomolecules for Neurodegenerative Disabilities. Biomolecules 2023; 13(8): 1250 doi: 10.3390/biom13081250
33
Samuel Joshua Pragasam Sampath, Subha Narayan Rath, Nagasuryaprasad Kotikalapudi, Vijayalakshmi Venkatesan. Beneficial effects of secretome derived from mesenchymal stem cells with stigmasterol to negate IL-1β-induced inflammation in-vitro using rat chondrocytes—OA management. Inflammopharmacology 2021; 29(6): 1701 doi: 10.1007/s10787-021-00874-z
34
Sumara de Freitas, Edson Naoto Makiyama, Bruna Roberta Oliveira Neves, Iolanda Silva Rafael Pizzolato Cezar, Carlos Eduardo da Silva Gonçalves, Marcelo Macedo Rogero, Ricardo Ambrósio Fock. The Influence of Cyanidin‐3‐Glucoside on the Modulation of Immune Cell Responses by Mesenchymal Stem Cell‐Conditioned Medium. Cell Biochemistry and Function 2025; 43(2) doi: 10.1002/cbf.70059
35
Luigi Donato, Concetta Scimone, Simona Alibrandi, Sergio Zaccaria Scalinci, Domenico Mordà, Carmela Rinaldi, Rosalia D'Angelo, Antonina Sidoti. Human retinal secretome: A cross-link between mesenchymal and retinal cells. World Journal of Stem Cells 2023; 15(7): 665-686 doi: 10.4252/wjsc.v15.i7.665
36
Qing Zhu, Yuansong Liao, Zhimin Liao, Guogen Ye, Ce Shan, Han Huang. Compact bone mesenchymal stem cells-derived paracrine mediators for cell-free therapy in sepsis. Biochemical and Biophysical Research Communications 2024; 727: 150313 doi: 10.1016/j.bbrc.2024.150313
37
Bárbara Torrecillas-Baena, Victoria Pulido-Escribano, Gabriel Dorado, María Ángeles Gálvez-Moreno, Marta Camacho-Cardenosa, Antonio Casado-Díaz. Clinical Potential of Mesenchymal Stem Cell-Derived Exosomes in Bone Regeneration. Journal of Clinical Medicine 2023; 12(13): 4385 doi: 10.3390/jcm12134385
38
Dailin Yuan, Ahmed El-Hashash. Joint and Bone. 2023; : 1 doi: 10.1016/B978-0-323-91938-8.00007-X
39
Liwen Wu, Longze Zhang, Minglei Huang, Yan Wu, Sikan Jin, Yaqi Zhang, Xinyun Gan, Ting Yu, Guang Yu, Jidong Zhang, Xianyao Wang. Mesenchymal Stem Cell-Derived Exosomes: Emerging as a Promising Cell-Free Therapeutic Strategy for Autoimmune Hepatitis. Biomolecules 2024; 14(11): 1353 doi: 10.3390/biom14111353
40
Faezeh Ebrahimi, Farzaneh Pirouzmand, Renzon Daniel Cosme Pecho, Mariam Alwan, Mohammed Yassen Mohamed, Mohammed Shnain Ali, Arezoo Hormozi, Sajedeh Hasanzadeh, Narges Daei, Zahra Hajimortezayi, Majid Zamani. Application of mesenchymal stem cells in regenerative medicine: A new approach in modern medical science. Biotechnology Progress 2023; 39(6) doi: 10.1002/btpr.3374
41
Adaleiz Ore, James M. Angelastro, Cecilia Giulivi. Integrating Mitochondrial Biology into Innovative Cell Therapies for Neurodegenerative Diseases. Brain Sciences 2024; 14(9): 899 doi: 10.3390/brainsci14090899
42
Daniel García-Sánchez, Alberto González-González, Itzíar Álvarez-Iglesias, Mónica del Dujo-Gutiérrez, Alfonso Bolado-Carrancio, Matilde Certo, María Isabel Pérez-Núñez, José A. Riancho, José Carlos Rodríguez-Rey, Jesús Delgado-Calle, Flor María Pérez-Campo. Engineering a Pro-Osteogenic Secretome through the Transient Silencing of the Gene Encoding Secreted Frizzled Related Protein 1. International Journal of Molecular Sciences 2023; 24(15): 12399 doi: 10.3390/ijms241512399
43
Basak Isildar, Serbay Ozkan, Hakan Sahin, Merve Ercin, Selda Gezginci-Oktayoglu, Meral Koyuturk. Preconditioning of human umbilical cord mesenchymal stem cells with deferoxamine potentiates the capacity of the secretome released from the cells and promotes immunomodulation and beta cell regeneration in a rat model of type 1 diabetes. International Immunopharmacology 2024; 129: 111662 doi: 10.1016/j.intimp.2024.111662
44
Beatrice Aramini, Valentina Masciale, Lorenzo Federico Zini Radaelli, Rossella Sgarzani, Massimo Dominici, Franco Stella. The sternum reconstruction: Present and future perspectives. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.975603
45
Anna Abbadessa, Alfredo Ronca, Aurelio Salerno. Integrating bioprinting, cell therapies and drug delivery towards in vivo regeneration of cartilage, bone and osteochondral tissue. Drug Delivery and Translational Research 2024; 14(4): 858 doi: 10.1007/s13346-023-01437-1
46
Ferenc Sipos, Györgyi Műzes. Disagreements in the therapeutic use of mesenchymal stem cell-derived secretome. World Journal of Stem Cells 2022; 14(6): 365-371 doi: 10.4252/wjsc.v14.i6.365
47
Luís Raposo, André P. Lourenço, Diana S. Nascimento, Rui Cerqueira, Nuno Cardim, Adelino Leite-Moreira. Human umbilical cord tissue-derived mesenchymal stromal cells as adjuvant therapy for myocardial infarction: a review of current evidence focusing on pre-clinical large animal models and early human trials. Cytotherapy 2021; 23(11): 974 doi: 10.1016/j.jcyt.2021.05.002
48
Jipeng Li, Mengting Wu, Lijie He. Immunomodulatory effects of mesenchymal stem cell therapy in chronic kidney disease: a literature review. BMC Nephrology 2025; 26(1) doi: 10.1186/s12882-025-04029-y
49
Kun-Chi Wu, Yu-Hsun Chang, Dah-Ching Ding, Shinn-Zong Lin. Mesenchymal Stromal Cells for Aging Cartilage Regeneration: A Review. International Journal of Molecular Sciences 2024; 25(23): 12911 doi: 10.3390/ijms252312911
50
S. V. Skupnevskiy, R. V. Saveljev, E. G. Pukhaeva, Ya. V. Morozova, S. M. Radaev, V. A. Smirnov, A. A. Grin. Mononuclear cells from human umbilical cord/placental blood: Assessment of allergenicity and impact on immune status in experimental warm-blooded animals. Medical Immunology (Russia) 2024; 27(2): 303 doi: 10.15789/1563-0625-MCF-3037
51
Melinda-Ildiko Mitranovici, Diana Maria Chiorean, Raluca Moraru, Liviu Moraru, Laura Caravia, Andreea Taisia Tiron, Marius Craina, Ovidiu Simion Cotoi. Understanding the Pathophysiology of Preeclampsia: Exploring the Role of Antiphospholipid Antibodies and Future Directions. Journal of Clinical Medicine 2024; 13(9): 2668 doi: 10.3390/jcm13092668
52
Ahmed El-Hashash. Joint and Bone. 2023; : 205 doi: 10.1016/B978-0-323-91938-8.00008-1
53
Natasha Salame, Jean-Pierre Bikorimana, Nehme El-Hachem, Wael Saad, Mazen Kurdi, Jing Zhao, Nicoletta Eliopoulos, Riam Shammaa, Moutih Rafei. UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells. Stem Cell Research & Therapy 2022; 13(1) doi: 10.1186/s13287-021-02693-z
54
Agnese Gugliandolo, Francesca Diomede, Jacopo Pizzicannella, Luigi Chiricosta, Oriana Trubiani, Emanuela Mazzon. Potential Anti-Inflammatory Effects of a New Lyophilized Formulation of the Conditioned Medium Derived from Periodontal Ligament Stem Cells. Biomedicines 2022; 10(3): 683 doi: 10.3390/biomedicines10030683
55
Patricia Semedo-Kuriki, Gabriel Pereira, Danilo Cândido de Almeida, Niels Olsen Saraiva Camara. Possibilities and Limitations in Current Translational Stem Cell Research. Biochemistry 2023; 44 doi: 10.5772/intechopen.109273
56
Victoria Pulido-Escribano, Bárbara Torrecillas-Baena, Marta Camacho-Cardenosa, Gabriel Dorado, María Ángeles Gálvez-Moreno, Antonio Casado-Díaz. Role of hypoxia preconditioning in therapeutic potential of mesenchymal stem-cell-derived extracellular vesicles. World Journal of Stem Cells 2022; 14(7): 453-472 doi: 10.4252/wjsc.v14.i7.453
57
Mazhar Mushtaq, Doaa Hussein Zineldeen, Muhammad Abdul Mateen, Khawaja Husnain Haider. Mesenchymal stem cells’ “garbage bags” at work: Treating radial nerve injury with mesenchymal stem cell-derived exosomes. World Journal of Stem Cells 2024; 16(5): 467-478 doi: 10.4252/wjsc.v16.i5.467
58
Sohil Amin, Hamed Massoumi, Deepshikha Tewari, Arnab Roy, Madhurima Chaudhuri, Cedra Jazayerli, Abhi Krishan, Mannat Singh, Mohammad Soleimani, Emine E. Karaca, Arash Mirzaei, Victor H. Guaiquil, Mark I. Rosenblatt, Ali R. Djalilian, Elmira Jalilian. Cell Type-Specific Extracellular Vesicles and Their Impact on Health and Disease. International Journal of Molecular Sciences 2024; 25(5): 2730 doi: 10.3390/ijms25052730
59
Robert M. Rusch, Emi Inagaki, Hiroko Taniguchi, Saki Sakakura, Rie Tamai, Hidenori Nonaka, Shota Shimizu, Shinri Sato, Yoko Ogawa, Hirayama Masatoshi, Kazuno Negishi, Hideyuki Okano, Shigeto Shimmura. Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation. The Ocular Surface 2024; 34: 523 doi: 10.1016/j.jtos.2024.11.001
60
Jafar Rezaie, Vahid Nejati, Monireh Mahmoodi, Mahdi Ahmadi. Mesenchymal stem cells derived extracellular vesicles: A promising nanomedicine for drug delivery system. Biochemical Pharmacology 2022; 203: 115167 doi: 10.1016/j.bcp.2022.115167
61
Yanan Li, Chaoran Liu, Guanghong Han. Research progress of odontogenic extracellular vesicles in regeneration of dental pulp. Oral Diseases 2023; 29(7): 2565 doi: 10.1111/odi.14451
62
Rita Hani, Luna Khayat, Abir Abdel Rahman, Nada Alaaeddine. Effect of stem cell secretome in skin rejuvenation: a narrative review. Molecular Biology Reports 2023; 50(9): 7745 doi: 10.1007/s11033-023-08622-y
63
Yinhua Song, Jiachen Wu, Yang Liu, Na Xu, Hualin Bai, Lingjuan Wang, Jihui Ai, Kezhen Li. The remodeling of ovarian function: targeted delivery strategies for mesenchymal stem cells and their derived extracellular vesicles. Stem Cell Research & Therapy 2024; 15(1) doi: 10.1186/s13287-024-03704-5
64
Laura Olmedo-Moreno, Yolanda Aguilera, Carmen Baliña-Sánchez, Alejandro Martín-Montalvo, Vivian Capilla-González. Heterogeneity of In Vitro Expanded Mesenchymal Stromal Cells and Strategies to Improve Their Therapeutic Actions. Pharmaceutics 2022; 14(5): 1112 doi: 10.3390/pharmaceutics14051112
65
Serbay Ozkan, Basak Isildar, Hakan Sahin, Halil Ibrahim Saygi, Dildar Konukoglu, Meral Koyuturk. Comparative analysis of effects of conditioned mediums obtained from 2D or 3D cultured mesenchymal stem cells on kidney functions of diabetic rats: Early intervention could potentiate transdifferentiation of parietal epithelial cell into podocyte precursors. Life Sciences 2024; 343: 122543 doi: 10.1016/j.lfs.2024.122543
66
Mohammad Rasouli, Fatemeh Safari, Raheleh Roudi, Navid Sobhani. Investigation of mesenchymal stem cell secretome on breast cancer gene expression: A bioinformatic approach to identify differentially expressed genes, functional networks, and potential therapeutic targets. Computational Biology and Chemistry 2025; 115: 108331 doi: 10.1016/j.compbiolchem.2024.108331
67
Seunghun Lee, Jeonghoon Heo, Eun-Kyung Ahn, Jae Hyun Kim, Young-Ho Kim, Hee-Kyung Chang, Sang-Joon Lee, Jongsik Kim, Seun-Ja Park. Conditioned secretome of adipose-derived stem cells improves dextran sulfate sodium-induced colitis in mice. World Journal of Gastroenterology 2021; 27(23): 3342-3356 doi: 10.3748/wjg.v27.i23.3342
68
Mohamed A. A. Hussein, Hosni A. M. Hussein, Ali A. Thabet, Karim M. Selim, Mervat A. Dawood, Ahmed M. El-Adly, Ahmed A. Wardany, Ali Sobhy, Sameh Magdeldin, Aya Osama, Ali M. Anwar, Mohammed Abdel-Wahab, Hussam Askar, Elsayed K. Bakhiet, Serageldeen Sultan, Amgad A. Ezzat, Usama Abdel Raouf, Magdy M. Afifi. Human Wharton’s Jelly Mesenchymal Stem Cells Secretome Inhibits Human SARS-CoV-2 and Avian Infectious Bronchitis Coronaviruses. Cells 2022; 11(9): 1408 doi: 10.3390/cells11091408
69
Payal Bhatnagar, Sherreen Elhariri, Ismail A S Burud, Nabil Eid. Perianal fistulizing Crohn’s disease: Mechanisms and treatment options focusing on cellular therapy. World Journal of Gastroenterology 2025; 31(9): 100221 doi: 10.3748/wjg.v31.i9.100221
70
Christian Ardianto, Robert Shen, Jimmy F.A. Barus, Poppy Kristina Sasmita, Yuda Turana, Lilis Lilis, Veronika Maria Sidharta. Secretome as neuropathology-targeted intervention of Parkinson’s disease. Regenerative Therapy 2022; 21: 288 doi: 10.1016/j.reth.2022.08.003
71
FERENC SIPOS, GYÖRGYI MŰZES. Controversies in therapeutic application of mesenchymal stem cell-derived secretome. BIOCELL 2022; 46(4): 903 doi: 10.32604/biocell.2022.018200
72
Kevin Dzobo. Recent Trends in Multipotent Human Mesenchymal Stem/Stromal Cells: Learning from History and Advancing Clinical Applications. OMICS: A Journal of Integrative Biology 2021; 25(6): 342 doi: 10.1089/omi.2021.0049
73
Sepideh Zununi Vahed, Seyyedeh Mina Hejazian, William Ndjidda Bakari, Rebecca Landon, Virginie Gueguen, Anne Meddahi-Pellé, Fani Anagnostou, Abolfazl Barzegari, Graciela Pavon-Djavid. Milking mesenchymal stem cells: Updated protocols for cell lysate, secretome, and exosome extraction, and comparative analysis of their therapeutic potential. Methods 2025; 238: 40 doi: 10.1016/j.ymeth.2025.03.004
74
Bruna Lopes, Ana Catarina Sousa, Patrícia Sousa, Alícia de Sousa Moreira, André Filipe Coelho, Luís Atayde, António J. Salgado, Stefano Geuna, Rui Alvites, Ana Colette Maurício. In vitro evaluation of dental pulp stem cells for sciatic nerve regeneration: foundations for future in vivo applications. Frontiers in Cell and Developmental Biology 2025; 13 doi: 10.3389/fcell.2025.1528213
75
Ranya Ibrahim, Hillary Mndlovu, Pradeep Kumar, Samson A. Adeyemi, Yahya E. Choonara. Cell Secretome Strategies for Controlled Drug Delivery and Wound-Healing Applications. Polymers 2022; 14(14): 2929 doi: 10.3390/polym14142929
76
Priyamvada Amol Arte, Kanchanlata Tungare, Mustansir Bhori, Renitta Jobby, Jyotirmoi Aich. Treatment of type 2 diabetes mellitus with stem cells and antidiabetic drugs: a dualistic and future-focused approach. Human Cell 2023; 37(1): 54 doi: 10.1007/s13577-023-01007-0
77
Ludovica Barone, Matteo Gallazzi, Federica Rossi, Roberto Papait, Mario Raspanti, Piero Antonio Zecca, Luca Buonarrivo, Barbara Bassani, Giovanni Bernardini, Antonino Bruno, Rosalba Gornati. Human Dental Pulp Mesenchymal Stem Cell-Derived Soluble Factors Combined with a Nanostructured Scaffold Support the Generation of a Vascular Network In Vivo. Nanomaterials 2023; 13(17): 2479 doi: 10.3390/nano13172479
78
Daniel García-Sánchez, Alberto González-González, Ana Alfonso-Fernández, Mónica Del Dujo-Gutiérrez, Flor M Pérez-Campo. Communication between bone marrow mesenchymal stem cells and multiple myeloma cells: Impact on disease progression. World Journal of Stem Cells 2023; 15(5): 421-437 doi: 10.4252/wjsc.v15.i5.421
79
Rajiv Kumar, Magali Cucchiarin, Agnieszka Maria Jastrzębska, Gerardo Caruso, Johannes Pernaa, Zarrin Minuchehr. Computational Biology for Stem Cell Research. 2024; : 159 doi: 10.1016/B978-0-443-13222-3.00001-0
80
Friederike Kirschner, Danielle Arnold-Schild, Christian Leps, Mateusz Krzysztof Łącki, Matthias Klein, Yannic Chen, Annekathrin Ludt, Federico Marini, Can Kücük, Lara Stein, Ute Distler, Malte Sielaff, Thomas Michna, Kristina Riegel, Krishnaraj Rajalingam, Tobias Bopp, Stefan Tenzer, Hansjörg Schild. Modulation of cellular transcriptome and proteome composition by azidohomoalanine—implications on click chemistry–based secretome analysis. Journal of Molecular Medicine 2023; 101(7): 855 doi: 10.1007/s00109-023-02333-4
81
Julia K. Bar, Anna Lis-Nawara, Piotr Grzegorz Grelewski. Dental Pulp Stem Cell-Derived Secretome and Its Regenerative Potential. International Journal of Molecular Sciences 2021; 22(21): 12018 doi: 10.3390/ijms222112018
82
Francesca Della Sala, Gennaro Longobardo, Gianluca Lista, Francesco Messina, Assunta Borzacchiello. Effect of Hyaluronic Acid and Mesenchymal Stem Cells Secretome Combination in Promoting Alveolar Regeneration. International Journal of Molecular Sciences 2023; 24(4): 3642 doi: 10.3390/ijms24043642
83
Vitalii Moskalov. Effects of various xenogenic mesenchymal stem cell secretome fractions on the regenerative capacity of the liver in vitro. Bionatura 2023; 8(3): 1 doi: 10.21931/RB/2023.08.03.90
84
Hiromi Miwa, Robert Dimatteo, Joseph de Rutte, Rajesh Ghosh, Dino Di Carlo. Single-cell sorting based on secreted products for functionally defined cell therapies. Microsystems & Nanoengineering 2022; 8(1) doi: 10.1038/s41378-022-00422-x
85
Cecep Suhandi, Ahmed Fouad Abdelwahab Mohammed, Gofarana Wilar, Ali El-Rayyes, Nasrul Wathoni. Effectiveness of Mesenchymal Stem Cell Secretome on Wound Healing: A Systematic Review and Meta-analysis. Tissue Engineering and Regenerative Medicine 2023; 20(7): 1053 doi: 10.1007/s13770-023-00570-9
86
Basak Isildar, Serbay Ozkan, Meral Koyuturk. Therapeutic Potential of Mesenchymal Stem Cell‐Derived Conditioned Medium for Diabetes Mellitus and Related Complications. Advanced Therapeutics 2023; 6(12) doi: 10.1002/adtp.202300216
87
Azra Sakhawat, Sana Javaid Awan, Muhammad Umer Khan, Samiah Shahid, Tahir Maqbool, Hafiz Muhammad Zubair, Hina Manzoor, Samiullah Khan. In silico and in vitro analyses to investigate the effects of vitamin C on VEGF protein. Journal of Taibah University Medical Sciences 2024; 19(4): 775 doi: 10.1016/j.jtumed.2024.06.008
88
Raghavendra B. Narasimha, Singireddy Shreya, Vijay Anand Jayabal, Vikas Yadav, Prasana Kumar Rath, Bidyut Prava Mishra, Sudhakar Kancharla, Prachetha Kolli, Gowtham Mandadapu, Sudarshan Kumar, Ashok Kumar Mohanty, Manoj Kumar Jena. Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review. Veterinary Sciences 2025; 12(1): 67 doi: 10.3390/vetsci12010067
89
Agnese Gugliandolo, Luigia Fonticoli, Oriana Trubiani, Thangavelu S. Rajan, Guya D. Marconi, Placido Bramanti, Emanuela Mazzon, Jacopo Pizzicannella, Francesca Diomede. Oral Bone Tissue Regeneration: Mesenchymal Stem Cells, Secretome, and Biomaterials. International Journal of Molecular Sciences 2021; 22(10): 5236 doi: 10.3390/ijms22105236
90
Vincent S Gallicchio. Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-I. Journal of Regenerative Medicine & Biology Research 2024; : 1 doi: 10.46889/JRMBR.2024.5202
91
Sungho Shin, Seonjeong Lee, Sunyoung Choi, Narae Park, Yumi Kwon, Jaehoon Jeong, Shinyeong Ju, Yunsil Chang, Kangsik Park, Chulwon Ha, Cheolju Lee. Characterization of the Secretome of a Specific Cell Expressing Mutant Methionyl-tRNA Synthetase in Co-Culture Using Click Chemistry. International Journal of Molecular Sciences 2022; 23(12): 6527 doi: 10.3390/ijms23126527
92
Martha L. Arango-Rodríguez, Víctor Alfonso Solarte-David, Silvia M. Becerra-Bayona, Eduardo Callegari, Maria D. Paez, Claudia L. Sossa, Miguel Enrique Ochoa Vera, Ligia C. Mateus, Sergio Eduardo serrano, Andrea K. Ardila-Roa, Lady T. Giratá Viviescas. Role of mesenchymal stromal cells derivatives in diabetic foot ulcers: a controlled randomized phase 1/2 clinical trial. Cytotherapy 2022; 24(10): 1035 doi: 10.1016/j.jcyt.2022.04.002
93
Su-Jeong Oh, Tiep Tien Nguyen, Yoojin Seo, Hee-Jeong Park, Ji-Su Ahn, Ye Young Shin, Byung-Jae Kang, Min Jang, Junhyeung Park, Jee-Heon Jeong, Hyung-Sik Kim. Sustained release of stem cell secretome from nano-villi chitosan microspheres for effective treatment of atopic dermatitis. International Journal of Biological Macromolecules 2024; 277: 134344 doi: 10.1016/j.ijbiomac.2024.134344
94
Jacob G. Hodge, Heather E. Decker, Jennifer L. Robinson, Adam J. Mellott. Tissue‐mimetic culture enhances mesenchymal stem cell secretome capacity to improve regenerative activity of keratinocytes and fibroblasts in vitro. Wound Repair and Regeneration 2023; 31(3): 367 doi: 10.1111/wrr.13076
95
Ria Margiana, Rajendra Falah Adriansyah, Mohammad Ayodhia Soebadi, Reny I’tishom, Tania Graciana, Silvia W. Lestari. Impacts of UC-MSCS on the quality of sperm in asthenoteratozoospermia. Salud, Ciencia y Tecnología 2025; 5: 1104 doi: 10.56294/saludcyt20251104
96
Jacob R. Ball, Tara Shelby, Fergui Hernandez, Cory K. Mayfield, Jay R. Lieberman. Delivery of Growth Factors to Enhance Bone Repair. Bioengineering 2023; 10(11): 1252 doi: 10.3390/bioengineering10111252
97
Kshama Gupta, Ralph B. Perkerson, Tammee M. Parsons, Ramacharan Angom, Danilyn Amerna, Jeremy D. Burgess, Yingxue Ren, Pamela J. McLean, Debabrata Mukhopadhyay, Prasanna Vibhute, Zbigniew K. Wszolek, Abba C. Zubair, Alfredo Quiñones-Hinojosa, Takahisa Kanekiyo. Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage. Stem Cell Research & Therapy 2024; 15(1) doi: 10.1186/s13287-024-03847-5
98
Ilgiz Gareev, Ozal Beylerli, Albert Sufianov, Valentin Pavlov, Huaizhang Shi. Stromal vascular fraction cell therapy: A promising therapeutic method for intracerebral hemorrhage. Brain Hemorrhages 2025;  doi: 10.1016/j.hest.2025.01.002
Write to the Help Desk
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

California Corporate Number: 3537345