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Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 28, 2025; 31(44): 112576
Published online Nov 28, 2025. doi: 10.3748/wjg.v31.i44.112576
Risk factors with nomogram construction for moderate to severe pain after endoscopic full-thickness resection
Guo-Yao Sun, Teng-Jiao Gao, Yong Sun, Wen Jia, Zhuo Yang
Guo-Yao Sun, Teng-Jiao Gao, Yong Sun, Wen Jia, Zhuo Yang, Department of Endoscopy, General Hospital of Northern Theater Command, Shenyang 110000, Liaoning Province, China
Co-first authors: Guo-Yao Sun and Teng-Jiao Gao.
Co-corresponding authors: Yong Sun and Zhuo Yang.
Author contributions: Sun GY contributed to data curation and visualization; Gao TJ performed formal analysis and software development; Sun GY and Gao TJ contributed equally to this article, they are the co-first authors of this manuscript; Jia W contributed to methodology and manuscript editing; Sun Y and Yang Z were responsible for conceptualization and supervision, they contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Supported by the Shenyang Bureau of Science and Technology, No. 22-321-32-15.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the General Hospital of Northern Theater Command, approval No. Y (2025) 332.
Informed consent statement: This retrospective study used existing clinical data and was approved by the Ethics Committee, with informed consent waived.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data generated in this study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhuo Yang, Chief Physician, Professor, Department of Endoscopy, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenhe District, Shenyang 110000, Liaoning Province, China. yangzhuocy@163.com
Received: July 31, 2025
Revised: September 6, 2025
Accepted: October 20, 2025
Published online: November 28, 2025
Processing time: 120 Days and 13.9 Hours
Core Tip

Core Tip: Endoscopic full-thickness resection (EFTR) is increasingly used for gastrointestinal lesion treatment but is often complicated by moderate to severe postoperative pain. This retrospective study identifies key risk factors, including body mass index, lesion size, and lesion nature, associated with postoperative pain after EFTR. A novel nomogram was developed to predict individual patient risk, demonstrating strong predictive accuracy and clinical utility. This tool may guide personalized pain management strategies, improving patient recovery and quality of life after EFTR.