Response to Korean medicine with acupotomy in patients with cognitive impairment in primary care: A multicenter registry protocol

Table 1 Study schedule of the registry study

	Study period
	Screening	Post-screening
Timepoint (month ± day)	To (0)	T1 (0 + 14)6	T2 (3 ± 30)	T3 (6 ± 30)	T4 (9 ± 30)	T5 (12 ± 30)
Screening
Informed consent	X
Inclusion/exclusion criteria	X
Assign participant number	X
Personal information1	X
Sociodemographic information2	X
Medication history3	X
Height and weight	X
Vital signs4	X
Assessments
MoCA-K		X	X	X	X	X
K-ECog-12		X	X	X	X	X
NRS		X	X	X	X	X
ISI-K		X	X	X	X	X
Korean medicine treatment5			X	X	X	X
Changes in medical and medication history			X	X	X	X
Adverse events			X	X	X	X

¹Collect name, date of birth, age, and sex.

²Gather details about the chief complaint (disease code and date of first visit) and sociodemographic data (smoking history, alcohol consumption, physical activity, family medical history, education level, past and current occupation, marital status, presence of depressive symptoms (Patient Health Questionnaire-2), and type of insurance coverage).

³Review the past 3 years of medication history, focusing on medications for hypertension, diabetes, dyslipidemia, stroke, heart disease, depression, insomnia, and cognitive impairment, and confirm if these medications are still being taken.

⁴Measure vital signs, including body temperature, blood pressure (systolic and diastolic), and pulse rate.

⁵Evaluation of treatment interventions, duration, and frequency over a 3-month period.

⁶Assessments at T1 will be performed only on participants who have successfully passed the screening.

K-ECog-12: Short form of Korean-everyday cognition; MoCA-K: Montreal Cognitive Assessment-Korean; NRS: Numeric Rating Scale; T: Time point; ISI-K: Korean version of the Insomnia Severity Index.