Clinicopathological differences between patients with schistosomal appendicitis and non schistosomal appendicitis: A retrospectively study of past ten years

Table 1 Proportion of schistosomal appendicitis in total appendicitis treated in the First Affiliated Hospital of Wannan Medical College from October 2013 to October 2023

Date	SA group (n)	NSA group (n)	SA proportion (%)
October 2013 to October 2014	11	495	2.20
October 2014 to October 2015	16	537	2.90
October 2015 to October 2016	9	487	1.80
October 2016 to October 2017	11	572	1.90
October 2017 to October 2018	20	565	3.40
October 2018 to October 2019	17	535	3.10
October 2019 to October 2020	11	568	1.90
October 2020 to October 2021	8	507	1.60
October 2021 to October 2022	17	555	3.00
October 2022 to October 2023	16	597	2.60

SA: Schistosomal appendicitis; NSA: Non schistosomal appendicitis.

Table 2 Analysis of general data and pathological types of schistosomal appendicitis and non schistosomal appendicitis, n (%)

Group	SA group (n = 136)	NSA group (n = 5418)	χ2/Z	P value
Gender			40.753	< 0.001
Female	42 (30.1)	2601 (48)
Male	94 (69.9)	2818 (52)
Age, mean ± SD (years)	61.73 ± 15.335	35.8 ± 24.013	-12.722	< 0.001
Classification			33.234	< 0.001
Acute simple appendicitis	12 (8.8)	677 (12.6)
Acute suppurative appendicitis	42 (39.8)	2546 (47.2)
Gangrenous or perforated appendicitis	37 (27.2)	1303 (24.2)
Periappendicular abscess	0 (0)	2 (0)
Acute attack of chronic appendicitis	45 (33.1)	862 (16)

SA: Schistosomal appendicitis; NSA: Non schistosomal appendicitis.

Table 3 Acute simple appendicitis

	β	SE	Wald	P value	95%CI
Schistosomal appendicitis	-0.389	0.305	1.626	0.202	0.678 (0.373-1.232)

CI: Confidence interval.

Table 4 Acute suppurative appendicitis

	β	SE	Wald	P value	95%CI
Schistosomal appendicitis	-0.685	0.188	13.34	< 0.001	0.504 (0.349-0.728)

CI: Confidence interval.

Table 5 Gangrenous or perforated appendicitis

	β	SE	Wald	P value	95%CI
Schistosomal appendicitis	0.166	0.195	0.721	0.396	1.180 (0.805-1.731)

CI: Confidence interval.

Table 6 Periappendicular abscess

	β	SE	Wald	P value	95%CI
Schistosomal appendicitis	-13.299	3446.519	0	0.977	0 (0)

CI: Confidence interval.

Table 7 Acute attack of chronic appendicitis

	β	SE	Wald	P value	95%CI
Schistosomal appendicitis	0.961	0.186	26.684	< 0.001	2.614 (1.815-3.763)

CI: Confidence interval.

Table 8 Analysis of general situation and past history of patients with schistosomal appendicitis and non schistosomal appendicitis, n (%)

Group	SA group (n = 136)	NSA group (n = 136)	χ2/Z	P value
Gender			8.15	0.004
Female	42 (30.9)	65 (47.8)
Male	94 (69.1)	71 (52.2)
Age, mean ± SD (years)	61.73 ± 15.335	33.21 ± 22.974	-9.519	< 0.001
Smoking history	9 (7.5)	6 (4.4)	1.102	0.294
Drinking history	7 (5.8)	1 (0.7)	3.919	0.048
Hypertension history	16 (13.3)	10 (7.4)	2.499	0.114
Coronary heart disease history	9 (7.5)	5 (3.7)	1.803	0.179
Diabetes history	2 (1.7)	2 (1.7)	0	1

SA: Schistosomal appendicitis; NSA: Non schistosomal appendicitis.

Table 9 Analysis of clinical symptoms and complications of schistosomal appendicitis and non schistosomal appendicitis, n (%)

Group	SA group (n = 136)	NSA group (n = 136)	χ2/Z	P value
Fever	1 (0.8)	6 (4.4)	1.871	0.171
Nausea and vomiting	30 (25)	36 (26.5)	0.072	0.788
Abdominal pain	106 (88.3)	125 (91.9)	0.926	0.336
Diarrhea	0	1 (0.7)	0	1
Constipation	2 (1.7)	1 (0.7)	0.012	0.913
Peritonitis	76 (63.3)	83 (61)	0.144	0.705
Colorectal cancer	14 (11.7)	3 (2.2)	9.204	0.002

SA: Schistosomal appendicitis; NSA: Non schistosomal appendicitis.

Table 10 Colorectal cancer

	β	SE	Wald	P value	95%CI
Schistosomal appendicitis	1.627	0.648	6.294	0.012	5.087 (1.427-18.132)

CI: Confidence interval.

Table 11 Analysis of laboratory examination of schistosomal appendicitis and non schistosomal appendicitis, mean ± SD

Group	SA group (n = 136)	NSA group (n = 136)	Z/t	P value
WBC (109/L)	10.142 ± 3.638	9.382 ± 3.637	-2.033	0.042
RBC (1012/L)	3.432 ± 0.645	3.949 ± 0.587	-6.28	< 0.001
NEU (109/L)	8.691 ± 4.217	7.288 ± 3.3	-2.95	0.003
LYM (109/L)	1.185 ± 0.558	0.921 ± 0.492	-3.544	< 0.001
MO (109/L)	0.696 ± 0.366	0.571 ± 0.283	-2.68	0.007
EO (109/L)	0.115 ± 0.127	0.057 ± 0.283	-4.428	< 0.001
BA (109/L)	0.003 ± 0.018	0.01 ± 0.032	-1.83	0.067
HGB (g/L)	116.02 ± 16.829	120.81 ± 15.978	2.336	0.020
PLT (109/L)	196.40 ± 87.267	202.96 ± 67.237	-1.046	0.295
HCT	0.344 ± 0.048	0.358 ± 0.061	-2.045	0.041
TP (g/L)	61.839 ± 6.703	62.909 ± 6.57	1.154	0.250
ALB (g/L)	33.719 ± 5.279	36.515 ± 5.635	3.657	< 0.001
ALT (U/L)	19.13 ± 15.389	20.08 ± 16.346	-0.66	0.509
AST (U/L)	19.258 ± 8.855	22.184 ± 15.582	-1.789	0.074
Cr (μmol/L)	61.785 ± 16.525	56.303 ± 19.990	-0.679	0.498
Bun (μmol/L)	5.316 ± 4.435	4.807 ± 3.120	-2.204	0.028
UA (μmol/L)	274.439 ± 84.443	265.027 ± 96.503	-0.717	0.414
TC (mmol/L)	3.775 ± 0.776	21.747 ± 95.122	-1.192	0.233
TG (mmol/L)	1.164 ± 0.516	1.245 ± 0.560	-0.506	0.613
C-reactive protein (mg/L)	60.932 ± 46.672	61.546 ± 45.350	-0.443	0.658
PCT (ng/L)	1.15	0.273 ± 0.118	-1.414	0.4

WBC: White blood cells; RBC: Red blood cells; NEU: Neutrophils; LYM: Lymphocyte; MO: Monocyte; EO: Eosinophil; BA: Basophil; HGB: Haemoglobin; PLT: Platelet; HCT: Haematocrit; TP: Total proteins; ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; Cr: Creatinine; Bun: Blood urea nitrogen; UA: Uric acid; TC: Total cholesterol; TG: Triglyceride; PCT: Procalcitonin.