Retrospective Study
Copyright ©The Author(s) 2024.
World J Clin Cases. Sep 16, 2024; 12(26): 5893-5900
Published online Sep 16, 2024. doi: 10.12998/wjcc.v12.i26.5893
Table 1 Comparison of clinical data between two groups
Variable
Successful ventilation group (n = 68)
Failed ventilation group (n = 26)
t/χ2
P value
Male [n (%)]35 (51.47)16 (61.54)0.7680.381
Age (years)64.74 ± 4.2565.77 ± 4.481.0400.301
BMI (kg/m2)23.41 ± 2.1223.62 ± 2.150.4280.669
Complications [n (%)]
Hypertension39 (57.35)16 (61.54)0.1360.713
Asthma26 (38.24)12 (46.15)0.4900.484
Diabetes22 (32.35)11 (42.31)0.8180.366
Systolic pressure (mmHg)109.85 ± 21.09107.77 ± 13.190.4690.640
Mean arterial pressure (mmHg)91.98 ± 9.7990.85 ± 10.430.4960.621
Heart rate (times/min)83.79 ± 12.3788.92 ± 12.561.7900.077
Oxygen saturation (%)87.93 ± 4.0188.73 ± 5.390.7880.433
Respiratory rate (times/min)21.85 ± 3.2423.04 ± 3.361.5690.120
Hospital stays (d)8.89 ± 3.1411.46 ± 4.343.1720.002
Blood gas analysis results
pH7.32 ± 0.167.21 ± 0.152.9360.004
PaO2 (mmHg)47.69 ± 5.4146.69 ± 5.660.7900.432
PaCO2 (mmHg)62.21 ± 3.6966.54 ± 3.025.334< 0.001
PaO2/FiO298.35 ± 5.2496.32 ± 5.161.6870.095
Diaphragm ultrasound
DTF (%)24.18 ± 3.0219.12 ± 3.187.172< 0.001
DE (mm)21.02 ± 2.2617.42 ± 2.147.010< 0.001
TI (s)1.14 ± 0.191.06 ± 0.141.9200.058
E-T index2.39 ± 0.471.84 ± 0.335.411< 0.001
Table 2 Multivariate logistic regression analysis of predictive indicators for non-invasive ventilation outcome in acute exacerbation of chronic obstructive pulmonary disease patients
Index
β
SE
Wald
P value
OR
95%CI
Hospital stays0.2210.1561.9990.1571.2470.918-1.694
pH5.3672.7313.8610.0490.0050.000-0.986
PaCO20.8450.3505.8410.0160.4300.216-0.852
DTF0.5620.2196.6130.0100.5700.371-0.875
DE0.1900.2190.7580.3841.2100.788-1.857
E-T index2.4012.0201.4130.2340.0910.002-4.747
Table 3 Predictive efficacy of potential of hydrogen, partial pressure of carbon dioxide, and diaphragm thickening fraction for non-invasive ventilation outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease
Index
AUC
95%CI
P value
Sensitivity
Specificity
pH0.6900.576-0.8040.0050.8850.500
PaCO20.8330.745-0.920< 0.0010.9230.691
DTF0.8730.793-0.953< 0.0010.8080.809