Published online Sep 16, 2024. doi: 10.12998/wjcc.v12.i26.5893
Revised: June 7, 2024
Accepted: July 1, 2024
Published online: September 16, 2024
Processing time: 76 Days and 19.2 Hours
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is often combined with respiratory failure, which increases the patient's morbidity and mortality. Diaphragm ultrasound (DUS) has developed rapidly in the field of critical care in recent years. Studies with DUS monitoring diaphragm-related rapid shallow breathing index have demonstrated important results in guiding intensive care unit patients out of the ventilator. Early prediction of the indica
To explore the predictive value of DUS indexes for non-invasive ventilation outcome in patients with AECOPD.
Ninety-four patients with AECOPD who received mechanical ventilation in our hospital from January 2022 to December 2023 were retrospectively analyzed, and they were divided into a successful ventilation group (68 cases) and a failed ventilation group (26 cases) according to the outcome of ventilation. The clinical data of patients with successful and failed noninvasive ventilation were com
There were no significant differences in gender, age, body mass index, complications, systolic pressure, heart rate, mean arterial pressure, respiratory rate, oxygen saturation, partial pressure of oxygen, oxygenation index, or time of inspiration between patients with successful and failed mechanical ventilation (P > 0.05). The patients with successful noninvasive ventilation had shorter hospital stays and lower partial pressure of carbon dioxide (PaCO2) than those with failed treatment, while potential of hydrogen (pH), diaphragm thickening fraction (DTF), diaphragm activity, and diaphragm movement time were significantly higher than those with failed treatment (P < 0.05). pH [odds ratio (OR) = 0.005, P < 0.05], PaCO2 (OR = 0.430, P < 0.05), and DTF (OR = 0.570, P < 0.05) were identified to be independent factors influencing the outcome of mechanical ventilation in AECOPD patients.
The DUS index DTF can better predict the outcome of non-invasive ventilation in AECOPD patients.
Core Tip: There are few relevant literature reports on the predictive value of diaphragm ultrasound (DUS) indexes for mechanical ventilation therapy, so we conducted a study in which the clinical data of patients with successful and failed noninvasive ventilation were compared, and the independent predictors of noninvasive ventilation outcomes in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients were identified by multivariate logistic regression analysis. It was found that the DUS index DTF can better predict the outcome of non-invasive ventilation therapy in AECOPD patients.