Retrospective Cohort Study
Copyright ©The Author(s) 2023.
World J Clin Cases. Jul 16, 2023; 11(20): 4824-4832
Published online Jul 16, 2023. doi: 10.12998/wjcc.v11.i20.4824
Table 1 Patient characteristics, n (%)
Characteristics
Fracture group (n = 40)
Non-fracture group (n = 40)
P value
Age (mean ± SD, yr)67.5 ± 11.861.2 ± 12.20.024
Gender (Female)22 (55.0)22 (55.0)1.000
BMI (mean ± SD, kg/m²)22.8 ± 3.524.6 ± 3.70.004
Smoking history19 (47.5)9 (22.5)0.011
Alcohol consumption7 (17.5)9 (22.5)0.799
Glucocorticoid use4 (10.0)3 (7.5)0.737
BMD (mean ± SD, g/cm²)0.70 ± 0.130.85 ± 0.10< 0.001
Vertebral trabecular changes28 (70.0)18 (45.0)0.021
Previous vertebral fractures23 (57.5)8 (20.0)< 0.001
Table 2 Logistic regression analysis for fracture risk prediction
Variables
Univariable OR (95%CI)
P value
Multivariable OR (95%CI)
P value
Age (yr)1.04 (1.00-1.08)0.0441.04 (1.00-1.08)0.034
Gender (Female)0.62 (0.27-1.42)0.2580.32 (0.12-0.86)0.022
BMI (kg/m²)0.85 (0.76-0.95)0.0030.88 (0.78-1.00)0.046
Smoking history3.09 (1.29-7.41)0.0112.30 (0.87-6.10)0.092
BMD (g/cm²)0.01 (0.00-0.10)< 0.0010.02 (0.01-0.21)0.001
Vertebral trabecular changes2.80 (1.22-6.44)0.0164.29 (1.61-11.41)0.004
Previous vertebral fractures5.37 (2.12-13.60)< 0.0013.83 (1.59-9.22)0.003