Recurrence of acyclovir-resistant herpes encephalitis in an immunocompromised patient: A case report

doi:10.12998/wjcc.v13.i34.111438

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Dec 6, 2025 (publication date) through Dec 9, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Clin Cases. Dec 6, 2025; 13(34): 111438
Published online Dec 6, 2025. doi: 10.12998/wjcc.v13.i34.111438

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Figure 1 Diffusion-weighted image, magnetic resonance imaging. A: On hospital day 3, a high-intensity area between the left temporal lobe and insular cortex was confirmed; B: On hospital day 48, a high-intensity area around the right temporal lobe was newly confirmed; C: On hospital day 117, no new recurrence was confirmed.

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Figure 2 Clinical course of the patient. GCS: Glasgow Coma Scale; MRI: Magnetic resonance imaging; CSF: Cerebrospinal fluid; HSV: Herpes simplex virus; DNA: Deoxyribonucleic acid.

Citation: Usuda D, Furukawa D, Imaizumi R, Ono R, Kaneoka Y, Nakajima E, Kato M, Sugawara Y, Shimizu R, Inami T, Kawai K, Matsubara S, Tanaka R, Suzuki M, Shimozawa S, Hotchi Y, Osugi I, Katou R, Ito S, Mishima K, Kondo A, Mizuno K, Takami H, Komatsu T, Nomura T, Sugita M. Recurrence of acyclovir-resistant herpes encephalitis in an immunocompromised patient: A case report. World J Clin Cases 2025; 13(34): 111438
URL: https://www.wjgnet.com/2307-8960/full/v13/i34/111438.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i34.111438

Usuda D, Furukawa D, Imaizumi R, Ono R, Kaneoka Y, Nakajima E, Kato M, Sugawara Y, Shimizu R, Inami T, Kawai K, Matsubara S, Tanaka R, Suzuki M, Shimozawa S, Hotchi Y, Osugi I, Katou R, Ito S, Mishima K, Kondo A, Mizuno K, Takami H, Komatsu T, Nomura T, Sugita M. Recurrence of acyclovir-resistant herpes encephalitis in an immunocompromised patient: A case report. World J Clin Cases 2025; 13(34): 111438 [DOI: 10.12998/wjcc.v13.i34.111438]

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