Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report

doi:10.12998/wjcc.v13.i33.113560

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Nov 26, 2025 (publication date) through Jan 5, 2026

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Nov 26, 2025; 13(33): 113560
Published online Nov 26, 2025. doi: 10.12998/wjcc.v13.i33.113560

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Figure 1 Electrocardiogram at admission showing mild QTc prolongation (432 ms).

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Figure 2 Electrocardiogram at 15 hours post-ingestion showing ventricular tachycardia.

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Figure 3 Serial changes in serum Venlafaxine (black solid line), O-desmethylvenlafaxine (blue dashed line), and QTc (red dotted line). Shaded areas represent the therapeutic range (0.1-0.4 µg/mL) and the lethal range (≥ 9.5 µg/mL). ODV: O-desmethylvenlafaxine.

Citation: Mori K, Kamijo Y, Doi T, Abe H, Takeuchi I. Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report. World J Clin Cases 2025; 13(33): 113560
URL: https://www.wjgnet.com/2307-8960/full/v13/i33/113560.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i33.113560