Morbihan disease misdiagnosed as senile blepharoptosis and successfully treated with short-term minocycline and ketotifen: A case report

Figure 1 Clinical manifestations of the patient before and after treatment. A: Initial clinical presentation. Moderate ptosis (yellow lines), suspected edema inside bilateral upper eyelids and shallow glabellar wrinkles were observed; B: Seven days after treatment of minocycline and ketotifen. Erythema (yellow arrow) triggered by biopsy and obvious improvement of ptosis and deepened glabellar wrinkles; C: 40 days after treatment of minocycline and ketotifen. The bilateral eyelids basically recovered to the pre-illness state.

Figure 2 Biopsy specimen from patient's upper eyelid. A: Hematoxylin–eosin staining (×40) showing edema and dilated lymphatics in dermis (orange arrows). B: Increased infiltration of mast cell (orange arrows) in toluidine blue (×400).