Relationship between treatment types and blood–brain barrier disruption in patients with acute ischemic stroke: Two case reports

Figure 1 Diffusion-weighted imaging. Case 1, A and B: Diffusion-weighted imaging and perfusion-weighted imagingshow acute infarctions in the left temporal and insular lobes with no significant diffusion-weighted imaging-perfusion-weighted imaging mismatch, C: Magnetic resonance angiography shows occlusion of the M2 inferior trunk. Case 2, D and E: Diffusion-weighted imaging and perfusion-weighted imaging show acute infarctions in the left parietal and insular lobes with significant DWI-PWI mismatch; F: Digital subtraction angiography confirmed the occlusion of the M2 inferior trunk; G: After thrombectomy, reperfusion and good antegrade blood flow was confirmed.

Figure 2 Dynamic contrast-enhanced magnetic resonance imaging. A representative blood-brain barrier permeability (K_trans) map of the patients without (A) and with (B) thrombectomy. The dashed line indicates the manually segmented stroke region with enhanced K_trans.