Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 6, 2022; 10(7): 2351-2356
Published online Mar 6, 2022. doi: 10.12998/wjcc.v10.i7.2351
Relationship between treatment types and blood–brain barrier disruption in patients with acute ischemic stroke: Two case reports
Youngbeom Seo, Jonghoon Kim, Min Cheol Chang, Hyungkyu Huh, Eun-Hee Lee
Youngbeom Seo, Jonghoon Kim, Department of Neurosurgery, College of Medicine, Yeungnam University, Daegu 42415, South Korea
Min Cheol Chang, Department of Rehabilitation Medicine, College of Medicine, Yeungnam University, Daegu 42415, South Korea
Hyungkyu Huh, Eun-Hee Lee, Medical Interdisciplinary Team, Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, South Korea
Author contributions: Kim J contributed to conception and design of the study; Huh H and Lee EH organized the database; Kim J and Seo Y wrote the first draft of the manuscript; Huh H, Kim J, Chang MC, and Seo J wrote sections of the manuscript; all authors contributed to manuscript revision, read, and approved the submitted version.
Supported by the National Research Foundation of Korea grant, No. 2019M3E5D1A02069399.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jonghoon Kim, MD, PhD, Doctor, Neurosurgeon, Professor, Department of Neurosurgery, College of Medicine, Yeungnam University, 170, Hyeonchung Street, Nam-Gu, Daegu 42415, South Korea. kjhns@yu.ac.kr
Received: October 12, 2021
Peer-review started: October 12, 2021
First decision: October 22, 2021
Revised: October 26, 2021
Accepted: January 17, 2022
Article in press: January 17, 2022
Published online: March 6, 2022
Processing time: 140 Days and 22.9 Hours
Core Tip

Core Tip: We describe two cases in which the usefulness of dynamic contrast-enhanced magnetic resonance imaging in detecting blood–brain barrier (BBB) disruption was evaluated after treatment of acute ischemic stroke using two different methods. Our cases suggest that BBB disruption could be important if BBB permeability is used to guide clinical treatment.