Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2021; 9(32): 9889-9895
Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.9889
Synchronous multiple primary malignancies of the esophagus, stomach, and jejunum: A case report
Yan Li, Lian-Song Ye, Bing Hu
Yan Li, Lian-Song Ye, Bing Hu, Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Li Y reviewed the literature and drafted the article; Ye LS provided critical revision to the manuscript; Hu B conceived the article; and all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient’s daughter for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bing Hu, MD, Professor, Department of Gastroenterology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan Province, China. hubingnj@163.com
Received: April 19, 2021
Peer-review started: April 19, 2021
First decision: June 23, 2021
Revised: June 26, 2021
Accepted: September 8, 2021
Article in press: September 8, 2021
Published online: November 16, 2021
Processing time: 204 Days and 11.3 Hours
Core Tip

Core Tip: This article presents a case with synchronous multiple primary malignancies, including esophageal squamous cell carcinoma, gastric adenocarcinoma, and jejunal stromal tumor. This patient had many cancer-related risk factors like heavy drinking, smoking, and family history. The high-risk jejunal stromal tumor was found during operation. Despite radical surgery and adjuvant chemotherapy, the patient died of widespread metastases 33 mo later. This case suggests a poor prognosis of synchronous multiple advanced primary malignancies and the importance of comprehensive assessment for high-risk populations.