Endothelial progenitor cells and coronary artery disease: Current concepts and future research directions

doi:10.12998/wjcc.v9.i30.8953

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Oct 26, 2021; 9(30): 8953-8966
Published online Oct 26, 2021. doi: 10.12998/wjcc.v9.i30.8953

Endothelial progenitor cells and coronary artery disease: Current concepts and future research directions

Sen-Tong Xiao, Chun-Yan Kuang

Sen-Tong Xiao, Department of Cardiovascular Diseases, People’s Hospital Affiliated to Guizhou Medical University, Guiyang 550003, Guizhou Province, China

Chun-Yan Kuang, Department of Cardiovascular Diseases, Guizhou Provincial People's Hospital, Guiyang 550003, Guizhou Province, China

Author contributions: Xiao ST wrote the manuscript; Kuang CY revised the article.

Supported by the Guizhou Science and Technology Department, No. Qian-Ke-He [2018]1097; the National Natural Science Foundation of China, No. 81560056; Program for Training Outstanding Young Scientific and Technological Talents of Guizhou Province, No. Qian Kehe Platform Talents [2019]5662; Program for the Scientific Activities of Selected Returned Overseas Professionals in Guizhou Province, No. Grant Qian-Ren [2018]0003; and Scientific and Technological Platform and Talent Team Project of Guizhou Province, No. Qian Kehe Platform Talents [2017]5405.

Conflict-of-interest statement: The authors report that they have no conflicting interests.

Corresponding author: Chun-Yan Kuang, MD, PhD, Chief Physician, Department of Cardiovascular Diseases, Guizhou Provincial People's Hospital, No. 83 Zhongshan East Road, Guiyang 550003, Guizhou Province, China. xiaokcy@sina.com

Received: March 26, 2021
Peer-review started: March 26, 2021
First decision: May 12, 2021
Revised: May 12, 2021
Accepted: August 18, 2021
Article in press: August 18, 2021
Published online: October 26, 2021
Processing time: 208 Days and 14.6 Hours

Core Tip

Core Tip: The development of clinical applications of endothelial progenitor cells (EPCs) has progressed in recent decades. In this review, we summarize and discuss the origins and antibody markers of EPCs and the clinical effects of EPC stents and infusion. We hope to predict future clinical uses of EPCs.