Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2021; 9(26): 7825-7832
Published online Sep 16, 2021. doi: 10.12998/wjcc.v9.i26.7825
Rare neonatal malignant primary orbital tumors: Three case reports
Yan Zhang, Yue-Yue Li, Han-Yang Yu, Xiao-Li Xie, Hui-Min Zhang, Fang He, Hong-Yang Li
Yan Zhang, Han-Yang Yu, Hui-Min Zhang, Department of Ophthalmology, The Seventh Medical Center of PLA General Hospital, Beijing 100700, China
Yue-Yue Li, Department of Ophthalmology, The Third Medical Center of PLA General Hospital, Beijing 100039, China
Xiao-Li Xie, Department of Pathology, The Seventh Medical Center of PLA General Hospital, Beijing 100700, China
Fang He, Department of Ophthalmology, The Eighth Medical Center of PLA General Hospital, Beijing 100842, China
Hong-Yang Li, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Author contributions: Zhang Y contributed conceptualization; He F contributed data curation; Li YY contributed formal analysis; Zhang Y contributed funding acquisition; Yu HY contributed project administration; Xie XL contributed resources; Zhang HM contributed supervision; Zhang Y wrote the original draft; Li HY reviewed and edited the manuscript; all authors read and approved the final manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Yang Li, MD, PhD, Doctor, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing 100050, China. faraway_sweet@163.com
Received: February 24, 2021
Peer-review started: February 24, 2021
First decision: April 13, 2021
Revised: April 20, 2021
Accepted: July 6, 2021
Article in press: July 6, 2021
Published online: September 16, 2021
Processing time: 197 Days and 20.3 Hours
Core Tip

Core Tip: The first case underwent routine chemotherapy following surgery but died within three months due to worsening condition as the tumor spread throughout the body. The other two children were treated by surgery, and at the follow-up visits 6 mo and 1 year after surgery, respectively, the wound was completed healed, and they had normal growth and development without radiotherapy or chemotherapy.