Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2021; 9(14): 3449-3457
Published online May 16, 2021. doi: 10.12998/wjcc.v9.i14.3449
Pure large cell neuroendocrine carcinoma originating from the endometrium: A case report
Ran Du, Feng Jiang, Zheng-Yan Wang, Yan-Qing Kang, Xiu-Yu Wang, Ying Du
Ran Du, Zheng-Yan Wang, Xiu-Yu Wang, Ying Du, Department of Pathology, Liaocheng People’s Hospital, Liaocheng 252000, Shandong Province, China
Feng Jiang, Department of Thoracic Surgery, Liaocheng Tumor Hospital, Liaocheng 252000, Shandong Province, China
Yan-Qing Kang, Department of Radiology, Liaocheng People’s Hospital, Liaocheng 252000, Shandong Province, China
Author contributions: Du R and Jiang J contributed to the work equally; Du R was a major contributor in reviewing literature and writing the manuscript; Jiang F analyzed and interpreted the patient data; Wang ZY, Wang XY, and Du Y performed the histological examination of the tumor and performed histological diagnosis; Kang YQ analyzed the patient’s magnetic resonance imaging data; All authors read and approved the final manuscript.
Informed consent statement: The present study was approved by the Ethics Committee of Liaocheng People’s Hospital, and written informed consent was obtained from the patient. Written informed consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: The authors report no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ying Du, MM, Doctor, Department of Pathology, Liaocheng People’s Hospital, No. 67 Dongchang West Road, Liaocheng 252000, Shandong Province, China. duying0309@163.com
Received: December 8, 2020
Peer-review started: December 8, 2020
First decision: January 24, 2021
Revised: February 10, 2021
Accepted: March 4, 2021
Article in press: March 4, 2021
Published online: May 16, 2021
Processing time: 142 Days and 6.8 Hours
Core Tip

Core Tip: We report the diagnostic and therapeutic experience of a 73-year-old patient with pure endometrial large cell neuroendocrine carcinoma. This article explores the histological features, differential diagnosis, treatment, and prognosis of this tumor and reviews the current literature of similar cases to provide a reference for the diagnosis and treatment of endometrial large cell neuroendocrine carcinoma.