Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2020; 8(12): 2566-2573
Published online Jun 26, 2020. doi: 10.12998/wjcc.v8.i12.2566
Demyelinating polyneuropathy and lymphoplasmacytic lymphoma coexisting in 36-year-old man: A case report
Lesia Rozłucka, Elżbieta Semik-Grabarczyk, Marta Pietrukaniec, Agnieszka Żak-Gołąb, Małgorzata Grabarczyk, Sebastian Grosicki, Michał Holecki
Lesia Rozłucka, Department of Internal Medicine, Allergology and Clinical Immunology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice 40-752, Poland
Elżbieta Semik-Grabarczyk, Marta Pietrukaniec, Agnieszka Żak-Gołąb, Michał Holecki, Department of Internal Medicine, Autoimmune and Metabolic Diseases, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice 40-752, Poland
Małgorzata Grabarczyk, Student Scientific Society at the Department of Internal Medicine, Autoimmune and Metabolic Diseases, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice 40-752, Poland
Sebastian Grosicki, Department of Hematology and Cancer Prevention, Faculty of Health Sciences in Bytom, Medical University of Silesia, Bytom, 41-902, Poland
Author contributions: Rozłucka L was patients’ doctor, drafted and prepared manuscript for final publication; Semik-Grabarczyk E and Grabarczyk M reviewed the literature and drafted the manuscript; Pietrukaniec M and Żak-Gołąb A contributed to manuscript drafting and translated the manuscript; Grosicki S performed hematology consultation and revised the manuscript; Holecki M was responsible for the revision of the manuscript for important intellectual content. All authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for hospitalization and performing diagnostic procedures.
Conflict-of-interest statement: None of the authors have any potential conflicts of interest to declare regarding this case report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Lesia Rozłucka, MD, Doctor, Department of Internal Medicine, Allergology and Clinical Immunology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Medykow 14, Katowice 40-752, Poland. lesia.rozlucka@gmail.com
Received: February 24, 2020
Peer-review started: February 24, 2020
First decision: April 24, 2020
Revised: May 20, 2020
Accepted: May 23, 2020
Article in press: May 23, 2020
Published online: June 26, 2020
Processing time: 120 Days and 7.7 Hours
Core Tip

Core tip: Lymphoplasmacytic lymphoma is a low-grade B cell type of non-Hodgkin's lymphoma. It occurs mainly in elderly, develops slowly and leads to malignant proliferation of lymphoid line cells in the bone marrow. In some cases, patients develop polyneuropathy, which may precede the general symptoms of lymphoma. We present a case of a young man with chronic inflammatory demyelinating polyneuropathy since 2012. His neurological condition worsened rapidly seven years later, which turned out to be paraneoplastic symptom of aggressive lymphoplasmacytic lymphoma. The lack of typical hematological symptoms resulted in delaying the diagnosis and fatal outcome.