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World J Clin Cases. Jun 6, 2020; 8(11): 2111-2115
Published online Jun 6, 2020. doi: 10.12998/wjcc.v8.i11.2111
Association between liver targeted antiviral therapy in colorectal cancer and survival benefits: An appraisal
Qiang Wang, Chao-Ran Yu
Qiang Wang, Chao-Ran Yu, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Shanghai 200025, China
Author contributions: Wang Q and Yu CR designed the research; Wang Q prepared the literature review and wrote the paper; Yu CR coordinated the reference review and performed the majority of the writing.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors who contributed their efforts in this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Chao-Ran Yu, MD, PhD, Surgeon, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, 270 Dongan Road, Shanghai 200025, China. chaoran_yu@yeah.net
Received: March 7, 2020
Peer-review started: March 7, 2020
First decision: March 24, 2020
Revised: April 10, 2020
Accepted: May 1, 2020
Article in press: May 1, 2020
Published online: June 6, 2020
Processing time: 93 Days and 3.1 Hours
Core Tip

Core tip: Liver metastasis is one of the major contributors to the cancer-related deaths in colorectal cancer. Previous studies reported that tumor cells rarely metastasize to the injured liver during the disease course. Others also identified survival benefits brought by antiviral therapy upon hepatocellular carcinoma. Hereby, this review discusses the potential impact of antiviral therapy in reducing liver metastasis of colorectal cancer.