Copyright
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 26, 2026; 14(6): 118545
Published online Feb 26, 2026. doi: 10.12998/wjcc.v14.i6.118545
Published online Feb 26, 2026. doi: 10.12998/wjcc.v14.i6.118545
Surgical management of acute choroidal neovascularization related submacular hemorrhage: Three case reports
Georges El Mollayess, Bachir Abiad, Department of Ophthalmology, Lebanese American University, Beirut 1100, Beyrouth, Lebanon
Mahmoud Jaroudi, Yehya Tlaiss, Rayan Itaoui, Bachir Abiad, Department of Ophthalmology, Clemenceau Medical Center, Beirut 1100, Beyrouth, Lebanon
Author contributions: El Mollayess G contributed to data curation; Jaroudi M contributed to conceptualization; investigation; Tlaiss Y contributed to study design; project administration; writing - original draft; Itaoui R contributed to investigation; data extraction; visualization (figures/tables); El Mollayess G and Abiad B contributed to surgical procedures/clinical oversight, supervision; Jaroudi M and Abiad B contributed to writing - review & editing.
Informed consent statement: Written informed consent was obtained from all patients for the surgical procedures and for publication of their clinical data and accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yehya Tlaiss, MD, Department of Ophthalmology, Clemenceau Medical Center, Hazmieh, The Backyard Street, Ghazal Hills, Beirut 1100, Beyrouth, Lebanon. yehyatlaiss@hotmail.com
Received: January 6, 2026
Revised: January 24, 2026
Accepted: February 5, 2026
Published online: February 26, 2026
Processing time: 39 Days and 7.7 Hours
Revised: January 24, 2026
Accepted: February 5, 2026
Published online: February 26, 2026
Processing time: 39 Days and 7.7 Hours
Core Tip
Core Tip: Acute submacular hemorrhage (SMH) secondary to choroidal neovascularization (CNV) is a vision-threatening emergency with no universal management consensus. This case series highlights the role of pars plana vitrectomy with subretinal tissue plasminogen activator, gas tamponade, and adjunct anti-vascular endothelial growth factor therapy for rapid foveal blood displacement. By integrating representative cases with contemporary evidence, we propose a practical, case-based treatment algorithm to guide timely surgical decision-making and postoperative management in severe CNV-related SMH.