Panda PK, Khan F. From contaminant to catastrophe: Applying integrated antimicrobial stewardship DIA model in a case. World J Clin Cases 2026; 14(23): 123883 [DOI: 10.12998/wjcc.123883]
Corresponding Author of This Article
Prasan Kumar Panda, MD, Division of Internal Medicine, All India Institute of Medical Sciences, College Block, Rishikesh 249203, Uttarākhand, India. motherprasanna@rediffmail.com
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Infectious Diseases
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editorial
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Panda PK, Khan F. From contaminant to catastrophe: Applying integrated antimicrobial stewardship DIA model in a case. World J Clin Cases 2026; 14(23): 123883 [DOI: 10.12998/wjcc.123883]
World J Clin Cases. Aug 16, 2026; 14(23): 123883 Published online Aug 16, 2026. doi: 10.12998/wjcc.123883
From contaminant to catastrophe: Applying integrated antimicrobial stewardship DIA model in a case
Prasan Kumar Panda, Fatima Khan
Prasan Kumar Panda, Division of Internal Medicine, All India Institute of Medical Sciences, Rishikesh 249203, Uttarākhand, India
Fatima Khan, Microbiology, Jawaharlal Nehru Medical Collge, Aligarh Muslim University, Aligarh 202006, Uttar Pradesh, India
Author contributions: Panda PK and Khan F searched the literature, drafted the manuscript statistically, critically reviewed it, and approved the study.
AI contribution statement: The authors take full responsibility and accountability for all content of this manuscript, including any portions for which AI tools were used as assistive technologies. All AI-assisted outputs were carefully reviewed, validated, and approved by the authors. AI tools were not used to generate original scientific data, perform independent scientific analyses, or draw scientific conclusions.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Prasan Kumar Panda, MD, Division of Internal Medicine, All India Institute of Medical Sciences, College Block, Rishikesh 249203, Uttarākhand, India. motherprasanna@rediffmail.com
Received: June 2, 2026 Revised: July 11, 2026 Accepted: July 27, 2026 Published online: August 16, 2026 Processing time: 73 Days and 7.9 Hours
Core Tip
Core Tip: Corynebacterium striatum, often dismissed as a contaminant, can cause severe and fatal infections in immunocompromised and device-dependent patients. This case demonstrates that adverse outcomes frequently result not from antimicrobial failure alone but from delayed integration of diagnostic, microbiological, device, therapeutic, and administrative stewardship measures. Integrated antimicrobial stewardship (IAS) provides a comprehensive framework for timely recognition, source control, multidisciplinary coordination, and optimized patient management. Implementing stewardship models, such as Society of Antimicrobial Stewardship PractIces’s 42 IAS practice points in form of DIA model and the PRESCRIBES framework, may improve clinical outcomes and reduce the burden of antimicrobial resistance in complex healthcare-associated infections.
