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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2025; 13(36): 114472
Published online Dec 26, 2025. doi: 10.12998/wjcc.v13.i36.114472
Published online Dec 26, 2025. doi: 10.12998/wjcc.v13.i36.114472
Cardiac arrest as initial presentation of Kawasaki disease with giant coronary aneurysms: A case report and review of literature
Dat Minh-Tan Truong, Liem Thanh Bui, Hieu Trong Pham, Bao Quoc Vo, Department of Intensive Care Unit, Children’s Hospital 2, Ho Chi Minh City 700000, Viet Nam
Liem Thanh Bui, Department of Pediatrics, University of Medicine and Pharmacy, Ho Chi Minh City 700000, Viet Nam
Tam Khiet Nguyen, Department of Cardiology, Children’s Hospital 2, Ho Chi Minh City 700000, Viet Nam
Thanh Tat Nguyen, Department of Infectious Diseases, Children’s Hospital 2, Ho Chi Minh City 700000, Viet Nam
Co-first authors: Dat Minh-Tan Truong and Liem Thanh Bui.
Author contributions: Truong DMT and Bui LT contributed equally to this manuscript and are co-first authors. Truong DMT, Bui LT, Vo BQ, and Nguyen TT contributed to the conceptualization; Truong DMT and Bui LT contributed to the data curation and funding acquisition; Nguyen TT was involved in the formal analysis; Truong DMT, Pham HT, and Nguyen TT participated in the investigation; Truong DMT, Bui LT, and Pham HT contributed to the methodology of this manuscript; Truong DMT, Bui LT, Pham HT, and Nguyen TT wrote the original draft; Truong DMT, Bui LT, Vo BQ, and Nguyen TT contributed to the critical revision of the final manuscript. All authors have contributed to and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Thanh Tat Nguyen, MD, PhD, Senior Researcher, Department of In
Received: September 22, 2025
Revised: October 20, 2025
Accepted: December 11, 2025
Published online: December 26, 2025
Processing time: 96 Days and 16 Hours
Revised: October 20, 2025
Accepted: December 11, 2025
Published online: December 26, 2025
Processing time: 96 Days and 16 Hours
Core Tip
Core Tip: Kawasaki disease (KD) is a childhood illness that can damage the heart if not recognized early. We describe a 19-month-old boy who developed fever, cough, and rash for almost a month, but was repeatedly treated as having infections. He suddenly went into cardiac arrest and was found to have severe heart vessel damage with clots from undiagnosed KD. He required prolonged resuscitation, advanced life support, and multiple treatments including cooling therapy, combined interventions of continuous renal replacement and plasma exchange. Remarkably, he recovered with good heart and brain function, showing the importance of early recognition and aggressive care in severe KD.