Editorial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 26, 2025; 13(3): 98110
Published online Jan 26, 2025. doi: 10.12998/wjcc.v13.i3.98110
Microplastic and nanoplastic exposure and risk of diabetes mellitus
Hui-Yi Hsiao, Chung-Yi Nien, Ruei-Feng Shiu, Wei-Chun Chin, Tzung-Hai Yen
Hui-Yi Hsiao, Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan
Hui-Yi Hsiao, Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, Taiwan
Chung-Yi Nien, Department of Life Sciences, National Central University, Zhongli 320317, Taoyuan, Taiwan
Ruei-Feng Shiu, Center of Excellence for The Oceans, National Taiwan Ocean University, Keelung 20224, Taiwan
Ruei-Feng Shiu, Institute of Marine Environment and Ecology, National Taiwan Ocean University, Keelung 20224, Taiwan
Wei-Chun Chin, Department of Chemical and Materials Engineering, University of California Merced, Merced, CA 95343, United States
Tzung-Hai Yen, Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou 33305, Taoyuan, Taiwan
Tzung-Hai Yen, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan
Author contributions: Hsiao HY was responsible for data collection and manuscript writing; Nien CY, Shiu RF and Chin WC were responsible for discussion of the manuscript; Yen TH was responsible for study design and supervision; all of the authors read and approved the final version of the manuscript to be published.
Supported by Research grant from Chang Gung Memorial Hospital, Linkou, Taiwan, No. CMRPG3N0622.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tzung-Hai Yen, MD, PhD, Doctor, Professor, Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, No. 5 Fu-Hsing Street, Kweishan, Linkou 33305, Taoyuan, Taiwan. m19570@adm.cgmh.org.tw
Received: June 18, 2024
Revised: September 28, 2024
Accepted: October 21, 2024
Published online: January 26, 2025
Processing time: 146 Days and 19.8 Hours
Core Tip

Core Tip: Laboratory studies provide strong evidence of the impacts of microplastic and nanoplastic exposure on glycolysis, blood glucose levels, insulin secretion, and insulin resistance. However, the lack of long-term human studies results in inconclusive conclusions regarding the direct effects of microplastics/nanoplastics on the risk of developing diabetes.