Sinha S, Nishant P, Morya AK, Sinha RK, Singh A. Intraocular pressure variation (ocular hypertension) in diabetes mellitus. World J Clin Cases 2025; 13(28): 107263 [DOI: 10.12998/wjcc.v13.i28.107263]
Corresponding Author of This Article
Arvind Kumar Morya, MD, Professor, Department of Ophthalmology, All India Institute of Medical Sciences, Bibi Nagar, Hyderabad 508126, Telangana, India. bulbul.morya@gmail.com
Research Domain of This Article
Ophthalmology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Sony Sinha, Department of Ophthalmology Vitreo-Retina, Neuro-Ophthalmology and Oculoplasty, All India Institute of Medical Sciences, Patna 801507, Bihar, India
Prateek Nishant, Department of Ophthalmology Refractive Surgery, Uvea and Neuro Ophthalmology, Akhand Jyoti Eye Hospital, Saran 841219, Bihar, India
Arvind Kumar Morya, Department of Ophthalmology, All India Institute of Medical Sciences, Hyderabad 508126, Telangana, India
Ranjeet Kumar Sinha, Department of Community Medicine, Patna Medical College, Patna 800004, Bihar, India
Arshi Singh, Department of Ophthalmology, Guru Nanak Eye Center, New Delhi 110001, New Delhi, India
Author contributions: Morya AK conceptualized the research and provided the outline of the content; Morya AK, Sinha S and Nishant P provided intellectual content; Sinha S, Sinha RK and Singh A analysed the data and wrote the manuscript; Sinha S, Nishant P and Singh A revised the manuscript; all authors read and approved the final version of the manuscript and agree to be accountable for all the content presented therein.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Arvind Kumar Morya, MD, Professor, Department of Ophthalmology, All India Institute of Medical Sciences, Bibi Nagar, Hyderabad 508126, Telangana, India. bulbul.morya@gmail.com
Received: March 19, 2025 Revised: May 26, 2025 Accepted: July 22, 2025 Published online: October 6, 2025 Processing time: 141 Days and 13.6 Hours
Core Tip
Core Tip: Ocular hypertension (OHT), defined as increased intraocular pressure (IOP, > 21 mmHg) in eyes without optic disc changes or visual field changes, is a condition which puts an eye at higher risk of developing glaucomatous optic neuropathy. It is one of the important concerns in diabetes mellitus (DM) even in the eyes which do not have diabetic retinopathy (DR) changes. OHT can also be observed in eyes with DR where it can develop with or without antecedent vitreoretinal intervention. While IOP has been directly implicated as an independent risk factor for DR, the retinopathy in DM is also related to comorbidities, like hypertension and heart disease that are also correlated with OHT. The understanding of the complex interplay of pathophysiologic risk factors is important for early identification and management of patients predisposed to this condition.
