Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2025; 13(26): 107496
Published online Sep 16, 2025. doi: 10.12998/wjcc.v13.i26.107496
Gastrointestinal metastasis from invasive lobular carcinoma following breast cancer treatment: A case report
Ping-Ping Liu, Ling-Ling Sun, Xue Jing
Ping-Ping Liu, Xue Jing, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Ling-Ling Sun, Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Author contributions: Liu PP collected the materials, drafted the manuscript and contributed to the critical revision of the intellectual content; Sun LL provided pathological images and modified legend information; Jing X revised the manuscript and assisted in submitting the final manuscript; all authors gave final approval for the version to be submitted.
Informed consent statement: Informed written consent was agreed from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue Jing, MD, PhD, Professor, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 59 Haier Road, Jinjialing Street, Laoshan District, Qingdao 266000, Shandong Province, China. jingxue@qdu.edu.cn
Received: March 31, 2025
Revised: April 29, 2025
Accepted: June 7, 2025
Published online: September 16, 2025
Processing time: 114 Days and 19.5 Hours
Core Tip

Core Tip: It is uncommon for breast cancer to spread simultaneously to the stomach and intestinal tract. We report a case of a 52-year-old woman with metastatic lobular carcinoma in the gastrointestinal tract. This case highlights the critical role of multidisciplinary collaboration. Endoscopic biopsy combined with immunohistochemistry is essential to differentiate metastatic breast cancer from primary gastrointestinal malignancies, guiding timely systemic therapy.