Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2025; 13(17): 101593
Published online Jun 16, 2025. doi: 10.12998/wjcc.v13.i17.101593
Epithelioid angiosarcoma of the cervical spine: A case report
Yu-Han Nan, Cheng-Di Chiu, Wei-Liang Chen, Liang-Chi Chen, Chun-Chung Chen, Der-Yang Cho, Jeng-Hung Guo
Yu-Han Nan, Cheng-Di Chiu, Chun-Chung Chen, Der-Yang Cho, Jeng-Hung Guo, Department of Neurosurgery, China Medical University Hospital, Taichung 404327, Taiwan
Cheng-Di Chiu, Der-Yang Cho, Graduate Institute of Biomedical Science, China Medical University, Taichung 404328, Taiwan
Cheng-Di Chiu, Jeng-Hung Guo, Spine Center, China Medical University Hospital, Taichung 404327, Taiwan
Wei-Liang Chen, Department of Interventional and Diagnostic Neuroradiology, China Medical University Hospital, Taichung 404327, Taiwan
Liang-Chi Chen, Department of Pathology, China Medical University Hospital, Taichung 404327, Taiwan
Chun-Chung Chen, Graduate Institute of Integrated Medicine, China Medical University, Taichung 404328, Taiwan
Author contributions: Nan YH performed the literature reviews and wrote the manuscript; Guo JH performed the surgery and planned the research in the manuscript; Chiu CD, Chen WL, Chen LC, Chen CC and Cho DY provided refinement suggestions for this article and verified the correctness of the manuscript.
Informed consent statement: The study participant's legal guardian provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jeng-Hung Guo, MD, PhD, Chief Physician, Department of Neurosurgery, China Medical University Hospital, No. 2 Yude Road, Taichung 404327, Taiwan. cmuhd14299@gmail.com
Received: September 20, 2024
Revised: December 10, 2024
Accepted: January 23, 2025
Published online: June 16, 2025
Processing time: 151 Days and 4.9 Hours
Core Tip

Core Tip: Epithelioid angiosarcoma (EA) is an aggressive and rare malignant tumor, particularly with spinal involvement. This case report presents a case of cervical spinal EA in a 63-year-old male with a pathological fracture causing spinal cord compression. The patient underwent staged surgeries with decompressive laminectomy, corpectomy, and bone fusion, followed by radiotherapy. Despite aggressive management, the patient succumbed to acute respiratory distress syndrome. This case emphasizes the importance of early diagnosis, timely tumor decompression to prevent neurological deterioration, and the challenges in managing EA due to its high recurrence and metastasis rates. Further research is needed to improve therapeutic outcomes.