©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2025; 13(12): 100248
Published online Apr 26, 2025. doi: 10.12998/wjcc.v13.i12.100248
Published online Apr 26, 2025. doi: 10.12998/wjcc.v13.i12.100248
Concurrent occurrence of adenocarcinoma and urothelial carcinoma of the prostate: Coexistence mechanisms from multiple perspectives
Xu-Chang Liu, Chun Liu, The No. 1 Clinical Medical School, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
Yu-Xiang Liu, Department of Nephrology, Shanxi Provincial People’s Hospital, Taiyuan 030012, Shanxi Province, China
Co-corresponding authors: Yu-Xiang Liu and Chun Liu.
Author contributions: Liu XC designed the thematic framework of this editorial and wrote the first draft, gave an exhaustive review of the first draft of the editorial, made invaluable suggestions on revision, especially policy interpretation and argument elaboration and rewrote some of the main paragraphs; Liu YX was responsible for verifying all the data and facts quoted in the editorial and added relevant trend analysis within the industry. This is to ensure accuracy as much as possible, which actually enriched the editorial power of persuasion; Liu C resubmitted this revised editorial to the journal, be in touch with the editor from the journal, and make sure the other authors' contributions are correctly included in the author contribution section.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.
Corresponding author: Chun Liu, Doctor, DPhil, Chief Doctor, Professor, Surgeon, The No. 1 Clinical Medical School, Shanxi Medical University, No. 56 Xinjian South Road, Taiyuan 030001, Shanxi, China. sxtyliuchun@126.com
Received: August 11, 2024
Revised: November 29, 2024
Accepted: December 19, 2024
Published online: April 26, 2025
Processing time: 149 Days and 1.7 Hours
Revised: November 29, 2024
Accepted: December 19, 2024
Published online: April 26, 2025
Processing time: 149 Days and 1.7 Hours
Core Tip
Core Tip: This article delves deeply into the mechanisms underlying the coexistence of prostate adenocarcinoma and urothelial carcinoma, encompassing the intricate interplay of androgen receptors, genetic mutations, and cellular signaling pathways. It elucidates the hypothesis that prostate cancer could potentially transition into urothelial carcinoma, offering fresh perspectives to inform clinical practice.