Meta-Analysis
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2024; 12(25): 5739-5748
Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5739
Prognostic significance of oligodendrocyte transcription factor 2 expression in glioma patients: A systematic review and meta-analysis
Peng-Cheng Li, De-Bo Yun, Ya-Xin Huang, Qian-Yi Huang
Peng-Cheng Li, De-Bo Yun, Department of Neurosurgery, The Affiliated Nanchong Central Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Ya-Xin Huang, Qian-Yi Huang, Department of Transfusion, The Affiliated Nanchong Central Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Author contributions: Li PC and Huang QY designed the research study; Li PC, Yun DB and Huang QY performed the research; Yun DB and Huang QY contributed analytic tools; Li PC, Huang QY and Huang YX analyzed the data and wrote the manuscript; All authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qian-Yi Huang, MAMS, Master’s Student, Staff Physician, Department of Transfusion, The Affiliated Nanchong Central Hospital of North Sichuan Medical College, No. 97 South Renmin Road, Shunqing District, Nanchong 637000, Sichuan Province, China. huangqianyi2019@163.com
Received: February 22, 2024
Revised: May 27, 2024
Accepted: June 24, 2024
Published online: September 6, 2024
Processing time: 145 Days and 15.9 Hours
Core Tip

Core Tip: The overall prognostic value of oligodendrocyte transcription factor 2 (Olig2) for glioma remains unclear. We performed the first meta-analysis of previously published studies related to the potential prognostic value of Olig2 in glioma patients to evaluate the association between Olig2 expression and the outcomes of glioma patients. Our findings suggest that high Olig2 expression may have a positive impact on the prognosis of glioma patients, and should be investigated further as a prognostic biomarker and therapeutic target for glioma.