©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2024; 12(22): 5131-5139
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.5131
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.5131
Clinical and genetic characteristics of a child with Sotos syndrome and attention-deficit/hyperactivity disorder: A case report
Ya-Jing Yang, Department of Internal Medicine, North China University of Science and Technology, Tangshan 063000, Hebei Province, China
Bei-Yi Li, Department of Internal Medicine, Hebei Medical University, Shijiazhuang 050017, Hebei Province, China
Ke-Xin Gan, Jing Liu, Xiu-Qin Lv, Dong-Mei Zhang, Department of Endocrinology, Hebei General Hospital, Shijiazhuang 050000, Hebei Province, China
Hui-Juan Ma, Department of Endocrinology, The First Hospital of Hebei Medical University, Shijiazhuang 050023, Hebei Province, China
Author contributions: Yang YJ, Li BY, Gan KX, Liu J, Lv XQ, and Zhang DM substantially contributed to the conception, design, and interpretation of the article and carefully revised important substantive content; Liu J and Ma HJ contributed to the final version of the manuscript. All authors have agreed to the publication of this manuscript.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this report.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised accordingly.
Corresponding author: Jing Liu, Doctor, Department of Endocrine, Hebei General Hospital, No. 348 Heping West Road, Xinhua District, Shijiazhuang 050000, Hebei Province, China.
Received: February 21, 2024
Revised: May 12, 2024
Accepted: June 7, 2024
Published online: August 6, 2024
Processing time: 132 Days and 0.5 Hours
Revised: May 12, 2024
Accepted: June 7, 2024
Published online: August 6, 2024
Processing time: 132 Days and 0.5 Hours
Core Tip
Core Tip: This case presents an overview of the clinical and mutational patterns observed in a pediatric patient diagnosed with Sotos syndrome and comorbid attention-deficit/hyperactivity disorder. Clinical features included accelerated growth, advanced skeletal maturation, and a normal intelligence quotient. Clinicians must remain aware of the potential for an attention-deficit/hyperactivity disorder diagnosis in Sotos syndrome patients to avoid missed diagnoses and to ensure the prompt provision of appropriate interventions, thereby improving patient quality of life and prognostic outcomes.