Retrospective Cohort Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2023; 11(26): 6040-6050
Published online Sep 16, 2023. doi: 10.12998/wjcc.v11.i26.6040
Clinical evaluation of ventilation mode on acute exacerbation of chronic obstructive pulmonary disease with respiratory failure
Jun-Jun Wang, Zhong Zhou, Li-Ying Zhang
Jun-Jun Wang, Department of Respiratory and Critical Care Medicine, The First People's Hospital of Yangquan City, Yangquan 045000, Shanxi Province, China
Zhong Zhou, Department of Respiratory and Critical Care Medicine, Guiyang Public Health Treatment Center, Guiyang 550001, Guizhou Province, China
Li-Ying Zhang, Department of Respiratory and Critical Care Medicine, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200023, China
Author contributions: Wang JJ and Zhou Z put forward the concept of this study; Zhang LY contributed to data collection; Zhou Z contributes to formal analysis; Wang JJ and Zhang LY participated in the survey; Wang JJ contributed to these methods; Zhou Z supervised research; Wang JJ verified this study; Zhang LY and Wang JJ contributed to the visualization of this study; Wang JJ, Zhang LY and Zhou Z reviewed and co-wrote the manuscript.
Institutional review board statement: This study was approved and reviewed by the Ethics Committee of the First People's Hospital of Yangquan City, Shanxi Province, No. YQLI2020081.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: We declare that there are no conflicts of interest in this study.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Ying Zhang, MD, Attending Doctor, Department of Respiratory and Critical Care Medicine, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 3rd Floor, Building 10, No. 639 Manufacturing Bureau Road, Huangpu District, Shanghai 200023, China. chui3897774213@126.com
Received: June 30, 2023
Peer-review started: June 30, 2023
First decision: July 18, 2023
Revised: July 19, 2023
Accepted: August 18, 2023
Article in press: August 18, 2023
Published online: September 16, 2023
Processing time: 70 Days and 0.3 Hours
Core Tip

Core Tip: Mechanical ventilation is a life-saving intervention for patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and respiratory failure. Volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) are two common modes of mechanical ventilation with different advantages and disadvantages. This study compared the efficacy and safety of VCV and PCV in patients with acute COPD exacerbation and respiratory failure. The results showed that both VCV and PCV were effective in treating patients with acute COPD exacerbation, but PCV was associated with lower peak airway pressures and a significant decrease in barotrauma, indicating that it might be a safer ventilation method for this group of patients. However, further large-scale studies are necessary to confirm these findings and identify the best ventilation approach for patients experiencing an acute COPD exacerbation. Clinicians should weigh the benefits and risks of each mode of mechanical ventilation when selecting a ventilation strategy.