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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2023; 11(22): 5365-5372
Published online Aug 6, 2023. doi: 10.12998/wjcc.v11.i22.5365
Published online Aug 6, 2023. doi: 10.12998/wjcc.v11.i22.5365
Individual with concurrent chest wall tuberculosis and triple-negative essential thrombocythemia: A case report
Xiao-Yan Xu, Jun Yuan, Xiao-Xia Zhang, Jie Yang, Department of Haematology, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China
Xiao-Yan Xu, Graduate School, Hebei North University, Zhangjiakou 075000, Hebei Province, China
Yong-Bin Yang, Department of Vascular Surgery, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China
Lin Kang, Department of Pathology, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China
Xiang-Shu Ma, Clinical Laboratory, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China
Author contributions: Xu XY, Yang YB, Yuan J, and Zhang XX, contributed to manuscript writing and editing, and data collection; Kang L and Ma XS contributed to data analysis; Yang J contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent for this case report has been obtained from the patient.
Conflict-of-interest statement: The authors report no conflicts of interest in this work.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Yang, Doctor, Associate Professor, Department of Haematology, Hebei General Hospital, No. 348 Heping West Road, Shijiazhuang 050051, Hebei Province, China. yjyyb313@163.com
Received: April 23, 2023
Peer-review started: April 23, 2023
First decision: June 15, 2023
Revised: June 25, 2023
Accepted: July 17, 2023
Article in press: July 17, 2023
Published online: August 6, 2023
Processing time: 102 Days and 0.3 Hours
Peer-review started: April 23, 2023
First decision: June 15, 2023
Revised: June 25, 2023
Accepted: July 17, 2023
Article in press: July 17, 2023
Published online: August 6, 2023
Processing time: 102 Days and 0.3 Hours
Core Tip
Core Tip: Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN) disorder resulting from genetic mutations in one or more common oncogenes. Here, we report the case of a 23-year-old male patient with a chest wall mass and extremely high platelet count, which remained extremely high even after surgical excision of the chest wall mass, chest wall tuberculosis (TB) diagnosis, and anti-TB combinatory drug therapy. Suppressor of cytokine signaling may be a novel MPN biomarker. Concurrent triple-negative ET and chest wall TB is uncommon, and its pathogenesis requires investigation.